Department of Clinical Psychology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Clinical Research Development Center, Imam Reza Hospital, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Lupus. 2024 Nov;33(13):1502-1510. doi: 10.1177/09612033241288011. Epub 2024 Sep 30.
Systemic Lupus Erythematosus (SLE) significantly affects both the quality of life related to health and non-health aspects. This study aims to evaluate the psychometric properties of the Persian version of the Lupus_PRO questionnaire, version 1.7. The questionnaire serves as a specific self-report outcome scale for assessing the treatment outcomes of Lupus disease.
The Lupus_PRO questionnaire, version 1.7, was translated into Persian using the standard forward-backward method. After being completed by 218 patients with Lupus, the psychometric properties of the instrument were examined. The Convergent and Discriminant Validity of the scale were assessed using Average Variance Extracted and Cross Loadings, respectively. The construct validity of the questionnaire was also evaluated through Confirmatory Factor Analysis (CFA). Cronbach's alpha was calculated to assess the reliability of the questionnaire dimensions.
Out of the 218 patients with lupus who participated in the current study, 13 (6%) were male, and 205 (94%) were female. The mean (SD) age of participants was 40.29 (10.94) years. The Average Variance Extracted (AVE) for HRQOL and Non-HRQOL constructs, except for the Coping and Cognition dimension, was greater than 0.50, indicating satisfactory convergent validity. The interdimensional correlation coefficient (Discriminant Validity) for each dimension with other questionnaire dimensions was less than 0.10, indicating that the questionnaire has good convergent and discriminant validity. Additionally, the results of the Confirmatory Factor Analysis (CFA) indicated that the questionnaire was a suitable fit. In terms of reliability, Cronbach's alpha for the various questionnaire dimensions ranged from 0.51 to 0.91, indicating good internal consistency.
The Persian version of the Lupus_PRO questionnaire, version 1.7, demonstrates acceptable validity and reliability in the Iranian population. This instrument can effectively measure various aspects of the quality of life in patients with lupus.
系统性红斑狼疮（SLE）显著影响与健康和非健康相关的生活质量。本研究旨在评估 Lupus_PRO 问卷第 1.7 版的波斯语版本的心理测量特性。该问卷是一种专门的自我报告量表，用于评估狼疮疾病的治疗结果。
使用标准的正向-反向翻译方法将 Lupus_PRO 问卷第 1.7 版翻译成波斯语。在 218 名狼疮患者完成问卷后，检查了该工具的心理测量特性。分别使用平均方差提取和交叉负荷来评估量表的收敛有效性和判别有效性。通过验证性因子分析（CFA）评估问卷的结构有效性。计算 Cronbach 的 alpha 来评估问卷维度的可靠性。
在参与本研究的 218 名狼疮患者中，有 13 名（6%）为男性，205 名（94%）为女性。参与者的平均（SD）年龄为 40.29（10.94）岁。除应对和认知维度外，HRQOL 和非 HRQOL 结构的平均方差提取（AVE）均大于 0.50，表明具有令人满意的收敛有效性。每个维度与其他问卷维度的维度间相关系数（判别有效性）小于 0.10，表明问卷具有良好的收敛和判别有效性。此外，验证性因子分析（CFA）的结果表明问卷具有良好的拟合度。在可靠性方面，各种问卷维度的 Cronbach 的 alpha 值在 0.51 至 0.91 之间，表明具有良好的内部一致性。
Lupus_PRO 问卷第 1.7 版的波斯语版本在伊朗人群中具有可接受的有效性和可靠性。该工具可以有效地衡量狼疮患者生活质量的各个方面。
