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[年龄与甲状腺功能(放射免疫研究)]

[Age and thyroid function (radioimmunologic study)].

作者信息

Zakharieva B

出版信息

Vutr Boles. 1985;24(4):91-6.

PMID:3934847
Abstract

Radio-immunologic study on the hormones of hypopheseal-thyroid axis was performed in 207 healthy subjects, aged from 0 to 79, namely: thyroxine (T4), triiodothyronine(T3) revrese T3 (rT3), thyrotropic hormone (TTH), thyroxine-binding globulin (TBG) and the index of free thyroxine was calculated (IFT4). Considerably elevated levels of thyroid indices were established at birth and only rT3 and TTH were normalized during the early neonatal period. The thyroid indices were also kept higher during the period of childhood and adolescence as compared with the mature and old age. A tendency was observed to a constant decrease of the levels of T3 and TBG with age advancing.

摘要

对207名年龄在0至79岁的健康受试者进行了垂体-甲状腺轴激素的放射免疫研究,具体如下:甲状腺素(T4)、三碘甲状腺原氨酸(T3)、反三碘甲状腺原氨酸(rT3)、促甲状腺激素(TTH)、甲状腺素结合球蛋白(TBG),并计算了游离甲状腺素指数(IFT4)。出生时甲状腺指标水平显著升高,仅rT3和TTH在新生儿早期恢复正常。与成年人和老年人相比,儿童和青少年时期的甲状腺指标也一直较高。随着年龄的增长,观察到T3和TBG水平呈持续下降趋势。

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