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翻修胃旁路术后静脉血栓栓塞事件:对2015年至2019年MBSAQIP数据库使用倾向匹配法的分析

Venous Thromboembolic Events Following Revisional Gastric Bypass: An Analysis of the MBSAQIP Database from 2015 to 2019 Using Propensity Matching.

作者信息

Economopoulos Konstantinos P, Szoka Nova, Eckhouse Shaina R, Chumakova-Orin Maryna, Kuchibhatla Maragatha, Merchant James, Seymour Keri A

机构信息

Duke University, Durham, NC, USA.

West Virginia University, Morgantown, WV, USA.

出版信息

Obes Surg. 2024 Dec;34(12):4358-4368. doi: 10.1007/s11695-024-07511-y. Epub 2024 Oct 1.

Abstract

BACKGROUND

Primary bariatric surgery is associated with moderate-to-high risk of venous thromboembolic events (VTE); however, the risk for revisional surgery lacks granularity. Our primary objective was to define the risk of VTE following revisional Roux-en-Y gastric bypass (RYGB) compared to primary RYGB.

METHODS

Adults who underwent primary or revision/conversion RYGB between January 1, 2015, and December 31, 2019, with a BMI ≥ 35 kg/m were identified in a bariatric specific database. VTE was defined as pulmonary embolus and/or deep venous thrombosis. Thirty-day VTE and transfusion rates were compared between the two groups using propensity score matching of 3:1.

RESULTS

Primary RYGB was performed in 197,186 (92.4%) patients compared to 16,144 (7.6%) in the revisional group. Patients in the revisional group had fewer comorbidities than those undergoing primary RYGB. In the matched cohort of 64,258 procedures, there were 48,116 (74.9%) primary RYGB cases compared to 16,142 (25.1%) RYGB revisions. The rate of VTE was similar in the revisional surgery group compared to the propensity matched primary RYGB group (0.4% vs. 0.3%, p > 0.580); however, transfusion was more common in the revisional group (1.4% vs. 1.0%, p = 0.005). Revisional group had higher rates of readmission, reoperation, increased length of stay, and operation length ≥ 180 min compared to matched primary RYGB group (p < 0.001).

CONCLUSIONS

VTE rates for both primary and revisional RYGB are similar. Revisional RYGB cases impose increased risk of bleeding among other outcomes. Thus, identifying those at higher risk of complications is critical.

摘要

背景

原发性减重手术与静脉血栓栓塞事件(VTE)的中高风险相关;然而,翻修手术的风险缺乏详细数据。我们的主要目标是确定翻修Roux-en-Y胃旁路术(RYGB)后发生VTE的风险,并与原发性RYGB进行比较。

方法

在一个减重手术专用数据库中,识别出2015年1月1日至2019年12月31日期间接受原发性或翻修/转换RYGB手术、BMI≥35kg/m²的成年人。VTE定义为肺栓塞和/或深静脉血栓形成。使用3:1的倾向评分匹配法比较两组的30天VTE和输血率。

结果

197,186例(92.4%)患者接受了原发性RYGB手术,而翻修组为16,144例(7.6%)。翻修组患者的合并症比接受原发性RYGB手术的患者少。在64,258例手术的匹配队列中,有48,116例(74.9%)原发性RYGB病例,相比之下,有16,142例(25.1%)RYGB翻修病例。与倾向评分匹配的原发性RYGB组相比,翻修手术组的VTE发生率相似(0.4%对0.3%,p>0.580);然而,输血在翻修组中更常见(1.4%对1.0%,p=0.005)。与匹配的原发性RYGB组相比,翻修组的再入院率、再次手术率、住院时间延长以及手术时间≥180分钟的发生率更高(p<0.001)。

结论

原发性和翻修性RYGB的VTE发生率相似。翻修性RYGB病例在其他结局中出血风险增加。因此,识别那些并发症风险较高的患者至关重要。

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