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2023 年,在埃塞俄比亚西北阿姆哈拉地区巴希尔巴市公立医院收治的成人道路交通伤害受害者中,生存状况及其预测因素的多中心回顾性随访研究。

Survival status and its predictors among adult victims of road traffic accident admitted to public hospitals of Bahir Bar City, Amhara regional state, Northwest, Ethiopia, 2023: multi center retrospective follow-up study.

机构信息

Amhara regional health Bureau, Northwest, Ethiopia.

Department of Adult Health Nursing, School of Health Sciences College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.

出版信息

BMC Emerg Med. 2024 Sep 30;24(1):177. doi: 10.1186/s12873-024-01093-9.

Abstract

INTRODUCTION

Road traffic accident is the most common cause of death in adults worldwide. Road traffic accident-related deaths increased from time to time in low- and middle-income countries including Ethiopia; however, there is limited evidence about Survival status and its predictors among adult victims of road traffic accidents admitted to Hospitals in Ethiopia specifically in the study area. Thus, this study aimed to assess Survival status and its predictors among adult victims of road traffic accident admitted to Hospitals.

METHODS

An institutional-based retrospective follow-up study was conducted from July 01/2019 to June 30/2022. A total of 402 samples were chosen using simple random sampling. Data was collected by a prepared checklist from the victims' chart and entered into Epi-Data version 4.6 software and then exported to STATA version 14.1 for analysis. Kaplan-Meier failure function and log-rank test were computed. The assumption was checked by Schoenfeld residual test. All variables in bivariable analysis, p-value < 0.25 were entered into multivariable cox-regression model. Adjusted Hazard Ratio with 95% Confidence Interval was reported to declare the strength of association and statistical significance p-value of < 0.05. Model fitness was checked by using Cox-Snell residual. Data was presented by text, table, and graph.

RESULT

The median survival time was 504 h. From all, 63(15.6%) deaths, 57% of deaths occurred between 24 and 168 h of follow-up with an overall incidence of 15.34deaths per10, 000 victims-hours observation. According to the Kaplan-Meier failure curve together with the log-rank test, the incidence density rate of death among victims who had a complication during admission was71.86per10,000victims-hour observation (95%, CI:53.66-96.25), which is different from those who did not have complication 5.17per10,000person-hour observation (95%, CI:3.26-8.21). The incidence density rate of death among victims who had low level of arterial oxygen saturation (SPO2 < 95%) during admission was 82.87per10, 000 victims-hour observation (95%, CI: 63.15-108.75), which is different from those who had arterial oxygen saturation ≥ 95% 3.16per10, 000victims -hour observation (95%, CI: 1.75-5.71) Develop complication (AHR = 3.1,95% CI:1.44-6.70), systolic blood pressure measurement value ≤ 89 mmHg (AHR = 2.4,95% CI:1.10-5.19), not admitted intensive care unit (AHR = 0.46,95% CI:0.022-0.97), Glasgow Coma Scale score ≤ 8 (AHR = 2.9,95% CI:1.07-7.75), Glasgow Coma Scale score 9-12(AHR = 3.8,95% CI:1.61-8.97) and, level of arterial oxygen saturation ≤ 95% (AHR = 6.5,95% CI:2.38-17.64) were predictors of outcome variable.

CONCLUSION AND RECOMMENDATIONS

The median survival time was short. Complication, low systolic blood pressure measurement value, low Glasgow Coma Scale score, not admit to intensive care unit and low level of arterial oxygen saturation were significant predictors of the outcome variable. So that healthcare providers better give special attention and care to those victims admitted to Hospitals. A further prospective study is recommended.

摘要

简介

道路交通伤害是全球成年人死亡的最常见原因。包括埃塞俄比亚在内的低收入和中等收入国家的道路交通伤害相关死亡人数不时增加;然而,关于特定于研究区域的埃塞俄比亚医院成年道路交通伤害受害者的生存状况及其预测因素的证据有限。因此,本研究旨在评估医院成年道路交通伤害受害者的生存状况及其预测因素。

方法

本研究采用回顾性随访研究,时间为 2019 年 7 月 1 日至 2022 年 6 月 30 日。采用简单随机抽样选择了 402 名样本。数据通过受害者图表的预编制检查表收集,并输入 Epi-Data 版本 4.6 软件,然后导出到 STATA 版本 14.1 进行分析。计算了 Kaplan-Meier 失败函数和对数秩检验。通过 Schoenfeld 残差检验检查了假设。单变量分析中所有 p 值<0.25 的变量均被纳入多变量 cox 回归模型。报告调整后的危害比及其 95%置信区间,以说明关联强度和统计显著性 p 值<0.05。使用 Cox-Snell 残差检查模型拟合度。数据以文字、表格和图形形式呈现。

结果

中位生存时间为 504 小时。在所有死亡病例中,63 例(15.6%)死亡,57%的死亡发生在随访的 24 至 168 小时之间,总死亡率为每 10000 名受害者-小时观察 15.34 例死亡。根据 Kaplan-Meier 失败曲线和对数秩检验,入院期间发生并发症的受害者的死亡率为每 10000 名受害者小时观察 71.86 例(95%CI:53.66-96.25),与无并发症的受害者不同,每 10000 名受害者小时观察 5.17 例(95%CI:3.26-8.21)。入院时动脉血氧饱和度(SPO2<95%)水平低的受害者的死亡率为每 10000 名受害者小时观察 82.87 例(95%CI:63.15-108.75),与动脉血氧饱和度≥95%的受害者不同,每 10000 名受害者小时观察 3.16 例(95%CI:1.75-5.71)。发生并发症(AHR=3.1,95%CI:1.44-6.70)、收缩压测量值≤89mmHg(AHR=2.4,95%CI:1.10-5.19)、未入住重症监护病房(AHR=0.46,95%CI:0.022-0.97)、格拉斯哥昏迷评分≤8(AHR=2.9,95%CI:1.07-7.75)、格拉斯哥昏迷评分 9-12(AHR=3.8,95%CI:1.61-8.97)和动脉血氧饱和度水平≤95%(AHR=6.5,95%CI:2.38-17.64)是结局变量的预测因素。

结论和建议

中位生存时间较短。并发症、收缩压测量值低、格拉斯哥昏迷评分低、未入住重症监护病房和低动脉血氧饱和度是结局变量的显著预测因素。因此,医护人员应更好地关注和照顾那些入住医院的受害者。建议进行进一步的前瞻性研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4ef/11443762/99c5834eebb4/12873_2024_1093_Fig1_HTML.jpg

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