Tanabe Naoto, Tokuda Satoshi, Nagai Erina, Katayama Hideyuki, Kanemoto Hideyuki
Department of Gastroenterological Surgery, Shizuoka General Hospital, Shizuoka, JPN.
Department of Cardiovascular Surgery, Shizuoka General Hospital, Shizuoka, JPN.
Cureus. 2024 Aug 30;16(8):e68251. doi: 10.7759/cureus.68251. eCollection 2024 Aug.
Solitary fibrous tumors (SFTs) are mesenchymal tumors, and retroperitoneal occurrence is rare. It has been identified in a variety of soft tissues and organs, such as the pleura, peritoneum, and meninges. In this case, the tumor was in contact with the abdominal aorta, and the invasion was difficult to judge preoperatively. Intraoperatively, it was revealed that the tumor could not be completely removed without aortic replacement. Although SFTs have a generally good prognosis, certain factors, such as tumor incomplete resection, have been reported to increase the risk of recurrence and metastasis. We were able to completely remove the tumor by performing a combined resection of the aorta. The specimens were microscopically disorganized proliferation of spindle-shaped cells. Immunostaining was positive for cluster of differentiation 34 (CD34) and signal transducer and activator of transcription 6 (STAT6). The tumor cells infiltrating into aortic adventitia were observed. This is a valuable case in which artificial blood vessel replacement was able to reduce the risk of recurrence and metastasis due to tumor remnants. We report a rare case of SFT resected with artificial blood vessel replacement.
孤立性纤维瘤(SFTs)是间叶组织肿瘤,发生于腹膜后的情况较为罕见。它已在多种软组织和器官中被发现,如胸膜、腹膜和脑膜。在本病例中,肿瘤与腹主动脉相连,术前难以判断是否存在侵犯。术中发现,如果不进行主动脉置换,肿瘤无法完全切除。尽管SFTs的总体预后良好,但据报道,某些因素,如肿瘤切除不完全,会增加复发和转移的风险。我们通过联合切除主动脉成功地完全切除了肿瘤。标本镜下显示梭形细胞呈无序增殖。免疫染色显示分化簇34(CD34)和信号转导及转录激活因子6(STAT6)呈阳性。观察到肿瘤细胞浸润至主动脉外膜。这是一个有价值的病例,人工血管置换能够降低因肿瘤残留导致的复发和转移风险。我们报告一例罕见的通过人工血管置换切除SFT的病例。