Sasaki Yoshimasa, Ikeda Tetsuya, Momose Yoshika, Yonemitsu Kenzo, Uema Masashi, Asai Tetsuo
National Institute of Health Sciences, 3-25-26, Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa 210-9501, Japan.
Division of Veterinary Science, Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Inada-cho, Obihiro, Hokkaido 080-8555, Japan.
Food Saf (Tokyo). 2024 Aug 30;12(3):59-66. doi: 10.14252/foodsafetyfscj.D-24-00002. eCollection 2024 Sep.
Chicken is a potent source of infection in humans. Occasionally, patients with severe enteritis require antimicrobial therapy. Antimicrobials are used to prevent and treat bacterial infections in broiler and breeder farms. Herein, we investigated the prevalence and antimicrobial resistance of in 337 vacuum-packed chicken breast products manufactured in Japan between June and December 2021. was isolated from 287 samples (85.2%). Among the products from Eastern Japan, the lowest prevalence was observed in those processed in September (65.6%), which was significantly ( < 0.05) lower than that in November or December. Among the products from Western Japan, the lowest prevalence was observed in those processed in August (61.9%), which was significantly ( < 0.05) lower than that in June, November, and December. The most frequent serovar was Schwarzengrund (223 isolates), followed by Infantis (53 isolates), Manhattan (9 isolates), and Enteritidis (1 isolate). High rates of antimicrobial resistance were observed for streptomycin (64.5%), kanamycin (50.2%), tetracycline (65.2%), nalidixic acid (11.5%), and trimethoprim (35.9%). Resistance rates against these five antimicrobials in . Schwarzengrund isolates were markedly higher in the isolates from Western Japan than in those from Eastern Japan. All 287 isolates were susceptible to ciprofloxacin which belongs to fluoroquinolones and cefotaxime which belongs to third-generation cephalosporins. prevalence in chicken products in Japan was found to be extremely high; therefore, chicken meat should be thoroughly heated before consumption. In Japan, fluoroquinolones and third-generation cephalosporins are recommended as the first- and second-choice antimicrobials for patients with severe enteritis, respectively. The results of this study show that administering fluoroquinolones or third-generation cephalosporins is an effective option for patients with enteritis caused by consuming chicken meat, and efficient strategies for management on broiler farms and chicken-processing plants need to be developed.
鸡肉是人类感染的一个重要来源。偶尔，患有严重肠炎的患者需要抗菌治疗。抗菌药物用于预防和治疗肉鸡和种鸡养殖场的细菌感染。在此，我们调查了2021年6月至12月在日本生产的337份真空包装鸡胸肉产品中[某种细菌]的流行情况和抗菌药物耐药性。从287份样本（85.2%）中分离出了[该细菌]。在日本东部的产品中，9月份加工的产品中[该细菌]的流行率最低（65.6%），显著低于11月或12月（P<0.05）。在日本西部的产品中，8月份加工的产品中[该细菌]的流行率最低（61.9%），显著低于6月、11月和12月（P<0.05）。最常见的血清型是施瓦岑格鲁德（223株分离株），其次是婴儿型（53株分离株）、曼哈顿型（9株分离株）和肠炎型（1株分离株）。观察到链霉素（64.5%）、卡那霉素（50.2%）、四环素（65.2%）、萘啶酸（11.5%）和甲氧苄啶（35.9%）的抗菌药物耐药率较高。施瓦岑格鲁德分离株对这五种抗菌药物的耐药率在日本西部的分离株中明显高于东部的分离株。所有287株[该细菌]分离株对属于氟喹诺酮类的环丙沙星和属于第三代头孢菌素类的头孢噻肟敏感。发现日本鸡肉产品中[该细菌]的流行率极高；因此，鸡肉在食用前应彻底加热。在日本，氟喹诺酮类和第三代头孢菌素类分别被推荐为严重[该细菌]肠炎患者的首选和次选抗菌药物。本研究结果表明，对于因食用鸡肉导致[该细菌]肠炎的患者，使用氟喹诺酮类或第三代头孢菌素类是一种有效的选择，并且需要制定肉鸡养殖场和鸡肉加工厂[该细菌]管理的有效策略。
