Duc Vu Minh, Shin Jiye, Nagamatsu Yamato, Fuhiwara Ayaka, Toyofuku Hajime, Obi Takeshi, Chuma Takehisa
Laboratory of Veterinary Public Health, Department of Veterinary Medicine, Joint Faculty of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan.
College of Economic and Technology, Thai Nguyen University, Group 15, Thinh Dan Ward, Thai Nguyen city, Thai Nguyen Province, Vietnam.
J Vet Med Sci. 2020 May 15;82(5):585-589. doi: 10.1292/jvms.20-0096. Epub 2020 Mar 25.
This study aimed to analyze the Salmonella serovars, measure the minimum inhibitory concentration of antimicrobials, and examine the antimicrobial resistance genes of Salmonella isolated from 192 broiler flocks in Kagoshima Prefecture in Japan, from 2013 to 2016. We found that all Salmonella isolates belonged to three serovars: Salmonella Manhattan, S. Infantis, and S. Schwarzengrund. Among them, S. Schwarzengrund prevalence has recently increased annually making the main serovar. Most recovered isolates were highly resistant to streptomycin, sulfamethoxazole, and oxytetracycline. We saw the reduction of third-generation cephalosporin resistance and identified the reason of increased kanamycin resistance to be the increased number of S. Schwazengrund isolates. Among the kanamycin-resistant Salmonella isolates, aphA1 constituted the main resistance gene detected.
本研究旨在分析日本鹿儿岛县192个肉鸡群在2013年至2016年间分离出的沙门氏菌血清型，测定抗菌药物的最低抑菌浓度，并检测沙门氏菌的抗菌耐药基因。我们发现所有沙门氏菌分离株均属于三个血清型：曼哈顿沙门氏菌、婴儿沙门氏菌和施瓦岑格伦德沙门氏菌。其中，施瓦岑格伦德沙门氏菌的流行率最近逐年上升，成为主要血清型。大多数回收的分离株对链霉素、磺胺甲恶唑和土霉素高度耐药。我们观察到第三代头孢菌素耐药性的降低，并确定卡那霉素耐药性增加的原因是施瓦岑格伦德沙门氏菌分离株数量的增加。在耐卡那霉素的沙门氏菌分离株中，aphA1是检测到的主要耐药基因。
