Tabesh Alireza, Antillon Ricardo Alberto, Kondradzhyan Manvel, Tan Ann Zera
Internal Medicine, Adventist Health White Memorial, Los Angeles, CA 90033, United States.
Family Medicine, UCLA, Los Angeles, CA 90024, United States.
World J Gastrointest Endosc. 2024 Sep 16;16(9):526-532. doi: 10.4253/wjge.v16.i9.526.
() is the most common chronic bacterial infection in humans. The risk of acquiring is related to socioeconomic status and living conditions early in life. Treatment regimens must consider local antibiotic resistance patterns. Adventist Health White Memorial Hospital serves a predominantly indigent population in east Los Angeles with a large number of immigrants from South and Central America. Data regarding the prevalence and resistance of in this population is scant.
To evaluate the prevalence and resistance of and correlate with country of origin.
All gastric biopsies were obtained by a single gastroenterologist at the hospital in a consecutive manner from patients with gastritis from 2017 to 2022 and sent to various labs for evaluation.
Two hundred and sixty-six patients are born in the United States, 450, 171, 70, and 30 patients are immigrants from Mexico, Central and South America (CSA), Asia, and other countries respectively. Overall, 14.65% were found to be infected with . Rates of infection in United States-born citizens, immigrants from Mexico, CSA, and Asia are 9.02%, 18.67%, 13.45%, and 11.43% respectively, with Mexican immigrants having a relative risk of 2.3889 [95% confidence interval (CI): 1.4789-3.8588, = 0.0004] compared to those born in United States. No correlation seen between infection and length of time immigrants were in United States. Relative risk of infection in patients with no proton pump inhibitor use within the past 30 days found to be 1.9276 (95%CI: 1.3562-2.7398, = 0.0003). Rates of resistance for clarithromycin and levofloxacin are 21.43% and 31.11%.
infection appears to be associated with low socioeconomic status and poor living conditions early in life. Clarithromycin and levofloxacin based treatment regimens should be avoided as first line therapy in this region, particularly in patients of Latin American origin.
（某种细菌）是人类最常见的慢性细菌感染。感染该细菌的风险与社会经济地位和早年生活条件有关。治疗方案必须考虑当地的抗生素耐药模式。复临健康白纪念医院主要服务于洛杉矶东部的贫困人口，其中有大量来自南美洲和中美洲的移民。关于该人群中该细菌的流行率和耐药性的数据很少。
评估该细菌的流行率和耐药性，并与原籍国相关联。
2017年至2022年期间，由医院的一名胃肠病学家连续从胃炎患者中获取所有胃活检样本，并送往不同实验室进行评估。
266名患者出生在美国，450名、171名、70名和30名患者分别是来自墨西哥、中南美洲（CSA）、亚洲和其他国家的移民。总体而言，发现14.65%的人感染了该细菌。美国出生的公民、来自墨西哥、CSA和亚洲的移民的感染率分别为9.02%、18.67%、13.45%和11.43%，与在美国出生的人相比，墨西哥移民的相对风险为2.3889[95%置信区间（CI）：1.4789 - 3.8588，P = 0.0004]。未发现感染与移民在美国的时间长短之间存在相关性。在过去30天内未使用质子泵抑制剂的患者中，感染的相对风险为1.9276（95%CI：1.3562 - 2.7398，P = 0.0003）。克拉霉素和左氧氟沙星的耐药率分别为21.43%和31.11%。
该细菌感染似乎与早年社会经济地位低和生活条件差有关。在该地区，应避免将基于克拉霉素和左氧氟沙星的治疗方案作为一线治疗，特别是对于拉丁裔患者。
