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接受血液透析和移植的终末期肾病患者的生活质量和心理困扰

Quality of life and psychological distress in end-stage renal disease patients undergoing hemodialysis and transplantation.

作者信息

Shdaifat Emad A, Abu-Sneineh Firas T, Ibrahim Abdallah M

机构信息

Community Nursing Department, Imam Abdulrahman Bin Faisal University, Dammam 1982, Saudi Arabia.

Department of Fundamental Nursing, Imam Abdulrahman Bin Faisal University, Dammam 1982, Saudi Arabia.

出版信息

World J Nephrol. 2024 Sep 25;13(3):95739. doi: 10.5527/wjn.v13.i3.95739.

DOI:10.5527/wjn.v13.i3.95739
PMID:39351185
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11439089/
Abstract

BACKGROUND

Among diverse profound impacts on patients' quality of life (QoL), end-stage renal disease (ESRD) frequently results in increased levels of depression, anxiety, and stress. Renal replacement therapies such as hemodialysis (HD) and transplantation (TX) are intended to enhance QoL, although their ability to alleviate psychological distress remains uncertain. This research posits the existence of a significant correlation between negative emotional states and QoL among ESRD patients, with varying effects observed in HD and TX patients.

AIM

To examine the relationship between QoL and negative emotional states (depression, anxiety, and stress) and predicted QoL in various end-stage renal replacement therapy patients with ESRD.

METHODS

This cross-sectional study included HD or TX patients in the Eastern Region of Saudi Arabia. The 36-item Short Form Survey and Depression Anxiety Stress Scale (DASS) was used for data collection, and correlation and regression analyses were performed.

RESULTS

The HD and TX transplantation groups showed statistically significant inverse relationships between QoL and DASS scores. HD patients with high anxiety levels and less education scored low on the physical component summary (PCS). In addition, the results of the mental component summary (MCS) were associated with reduced depression. Compared with older transplant patients, TX patients' PCS scores were lower, and depression, stress, and negative working conditions were highly correlated with MCS scores.

CONCLUSION

The findings of this study revealed notable connections between well-being and mental turmoil experienced by individuals undergoing HD and TX. The PCS of HD patients is affected by heightened levels of anxiety and lower educational attainment, while the MCS of transplant patients is influenced by advancing age and elevated stress levels. These insights will contribute to a more comprehensive understanding of patient support.

摘要

背景

终末期肾病(ESRD)对患者生活质量(QoL)有多种深远影响,常导致抑郁、焦虑和压力水平升高。血液透析(HD)和移植(TX)等肾脏替代疗法旨在提高生活质量,但其缓解心理困扰的能力仍不确定。本研究假定ESRD患者的负面情绪状态与生活质量之间存在显著相关性,在HD和TX患者中观察到不同的影响。

目的

探讨各种终末期肾脏替代治疗的ESRD患者的生活质量与负面情绪状态(抑郁、焦虑和压力)之间的关系以及预测的生活质量。

方法

这项横断面研究纳入了沙特阿拉伯东部地区的HD或TX患者。使用36项简短调查问卷和抑郁焦虑压力量表(DASS)收集数据,并进行相关性和回归分析。

结果

HD组和TX移植组的生活质量与DASS评分之间存在统计学上的显著负相关关系。焦虑水平高且教育程度低的HD患者在身体成分总结(PCS)方面得分较低。此外,心理成分总结(MCS)的结果与抑郁减轻有关。与老年移植患者相比,TX患者的PCS得分较低,抑郁、压力和负面工作条件与MCS得分高度相关。

结论

本研究结果揭示了接受HD和TX治疗的个体的幸福感与心理困扰之间的显著联系。HD患者的PCS受焦虑水平升高和教育程度较低的影响,而移植患者的MCS受年龄增长和压力水平升高的影响。这些见解将有助于更全面地理解患者支持。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ba9/11439089/bee7366681af/95739-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ba9/11439089/bee7366681af/95739-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ba9/11439089/bee7366681af/95739-g001.jpg

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