Department of Public Health and Preventive Medicine, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic.
Department of Pharmacology and Toxicology, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic.
Cent Eur J Public Health. 2024 Sep;32(3):200-204. doi: 10.21101/cejph.a8138.
The dietary composition is able to rapidly and significantly influence the diversity of the gut microbiome. This article focuses on how various types of diet affect the composition of the gut microbiome and how dietary changes are able to prevent or slow down the development of non-communicable diseases including obesity, type 2 diabetes mellitus, cardiovascular diseases, and low-grade inflammation.
A review in PubMed and a hand search using references in identified articles were performed. Studies published in English from 2000 to 2024 were included.
The studies showed the significant effect of diet on the development of non-communicable diseases dependent on the state of the gut microbiota and molecules it produces. The Western diet that continues to gain in popularity for Czech people, leads to dysbiosis and production of bacterial lipopolysaccharide or trimethylamine N-oxide causing systemic chronic inflammation in the body and thus promoting the development of non-communicable diseases.
Findings from this review emphasize the importance of healthy eating habits in the prevention of intestinal dysbiosis and still increasing prevalence and incidence of obesity and other non-communicable diseases.
饮食结构能够快速且显著地影响肠道微生物组的多样性。本文主要关注不同类型的饮食如何影响肠道微生物组的组成，以及饮食变化如何预防或减缓肥胖、2 型糖尿病、心血管疾病和低度炎症等非传染性疾病的发展。
在 PubMed 上进行了综述，并在手头上对已确定文章的参考文献进行了搜索。纳入了 2000 年至 2024 年发表的英文研究。
研究表明，饮食对非传染性疾病的发展有显著影响，这取决于肠道微生物群的状态及其产生的分子。捷克人越来越喜欢的西方饮食会导致肠道菌群失调和细菌脂多糖或三甲胺 N-氧化物的产生，从而导致全身性慢性炎症，进而促进非传染性疾病的发展。
本综述的研究结果强调了健康饮食习惯在预防肠道菌群失调以及肥胖症和其他非传染性疾病发病率和发生率不断上升方面的重要性。
