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适度体力活动及较高频率与中老年人群衰弱发生率呈负相关:一项在欧洲开展的4年纵向研究

Moderate physical activity and higher frequency are inversely associated with incidence of frailty in middle-aged and older population: a 4-year longitudinal study in Europe.

作者信息

Qiu Fanji, Yu Yichao, Li Jinfeng

机构信息

Movement Biomechanics, Institute of Sport Sciences, Humboldt-Universität zu Berlin, Unter den Linden 6, 10099, Berlin, Germany.

School of Sports Coaching, Beijing Sports University, Beijing, 100084, China.

出版信息

Eur Geriatr Med. 2024 Dec;15(6):1871-1879. doi: 10.1007/s41999-024-01073-z. Epub 2024 Oct 1.

Abstract

BACKGROUND

Global aging is leading to an increase in frailty patients, and physical activity (PA) may have an impact on frail in middle-aged and older population. This study aimed to explore the relationship between the frequency of different PA intensities and the incidence and prevalence of frailty in middle-aged and older adults based on the Survey of Health, Ageing, and Retirement in Europe (SHARE).

METHOD

Self-reported questionnaires were used to obtain information on demographics and PA, and frailty was assessed using the SHARE Frailty Instrument (SHARE-FI). Cox regression and logistic regression models were used to explore the association between PA and frailty and stratified according to middle or old age.

RESULTS

Among 6315 baseline non-frail participants aged 44-96 years, 16.1% developed frailty over 4 years, with higher incidence and prevalence in women (P < 0.05). Women accounting for 55.80% of the sample. The frequency of participants participating in sports decreased over 4 years (P < 0.05). Compared with participants who engaged in PA more than once a week, participants who engaged in moderated PA less frequently had a higher risk of new-onset frailty (HR: 3.174-6.115), and participants who engaged in vigorous PA 1-3 times a month had a higher risk of new-onset frailty (HR: 1.335). Participation in low-frequency moderate PA and vigorous PA 1-3 times per month were positively associated with the prevalence of frailty (P < 0.05).

CONCLUSION

Physical activity frequency decreases with age in middle-aged and older adults. Those adults who engage in moderate PA more than once a week have a lower risk of incidence of frailty, compared to those with more sedentary life-styles. Additionally, women need to pay more attention to frailty management.

摘要

背景

全球老龄化导致衰弱患者增多,身体活动(PA)可能对中老年人群的衰弱产生影响。本研究旨在基于欧洲健康、老龄化和退休调查(SHARE),探讨不同PA强度的频率与中老年成年人衰弱的发病率和患病率之间的关系。

方法

使用自我报告问卷获取人口统计学和PA信息,并使用SHARE衰弱量表(SHARE-FI)评估衰弱情况。采用Cox回归和逻辑回归模型探讨PA与衰弱之间的关联,并按中年或老年进行分层。

结果

在6315名年龄在44 - 96岁的基线非衰弱参与者中,16.1%在4年内出现衰弱,女性的发病率和患病率更高(P < 0.05)。女性占样本的55.80%。参与者参与运动的频率在4年内下降(P < 0.05)。与每周进行一次以上PA的参与者相比,较少进行适度PA的参与者新发衰弱风险更高(HR:3.174 - 6.115),每月进行1 - 3次剧烈PA的参与者新发衰弱风险更高(HR:1.335)。每月参与低频适度PA和每月1 - 3次剧烈PA与衰弱的患病率呈正相关(P < 0.05)。

结论

中老年成年人的身体活动频率随年龄增长而降低。与生活方式更久坐的成年人相比,每周进行一次以上适度PA的成年人衰弱发病率较低。此外,女性需要更多关注衰弱管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4086/11632035/1cc2d6cd8872/41999_2024_1073_Fig1_HTML.jpg

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