将巨大疱性肺气肿误诊为转移性腺癌：一例报告
Overdiagnosing giant bullous emphysema as metastatic adenocarcinoma: a case report.
作者信息
Lee Jiyun, Park Eunsu
机构信息
Department of Thoracic and Cardiovascular Surgery, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Department of Pathology, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
出版信息
J Cardiothorac Surg. 2024 Oct 1;19(1):564. doi: 10.1186/s13019-024-03112-z.
BACKGROUND
Giant bullous emphysema is characterized by large bullae occupying at least one-third of the hemithorax and leading to compression of the surrounding lung parenchyma. Overdiagnosis can occur because of the atypical appearance of hyperplastic type II pneumocytes, which may be mistaken for malignant cells.
CASE PRESENTATION
A 48-year-old male with a history of smoking and occupational exposure presented with dyspnea and drowsiness. Initial chest X-ray revealed a tension pneumothorax, and subsequent chest CT revealed extensive bullous emphysema and lung cancer in the right middle lobe (RML). Pathologic examination initially indicated resected bullae to metastatic adenocarcinoma, but upon review, it was determined that the reactive alveolar cells were misdiagnosed as malignant.
CONCLUSIONS
This case emphasizes the need for thorough histopathological assessment and prudent interpretation of atypical cellular morphology.
背景
巨大泡性肺气肿的特征是大泡占据至少一半胸腔并导致周围肺实质受压。由于II型增生性肺细胞的非典型外观，可能会发生过度诊断，其可能被误认为是恶性细胞。
病例报告
一名有吸烟和职业暴露史的48岁男性出现呼吸困难和嗜睡。最初的胸部X线检查显示张力性气胸，随后的胸部CT显示右中叶广泛的泡性肺气肿和肺癌。病理检查最初表明切除的大泡为转移性腺癌，但经复查，确定反应性肺泡细胞被误诊为恶性。
结论
本病例强调了对非典型细胞形态进行全面组织病理学评估和谨慎解读的必要性。
Zotero 插件