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异位动作电位的产生:其在慢性致痫灶中的发生情况。

Ectopic action potential generation: its occurrence in a chronic epileptogenic focus.

作者信息

Pinault D, Pumain R

出版信息

Exp Brain Res. 1985;60(3):599-602. doi: 10.1007/BF00236948.

DOI:10.1007/BF00236948
PMID:3935471
Abstract

Intracortical axon terminals of thalamocortical relay neurons projecting into chronic cortical epileptogenic foci may generate high frequency bursts of action potentials during spontaneous cortical epileptiform paroxysms. Such bursts occur regularly before onset of the corresponding surface paroxysms in a large proportion of the tested neurons. Therefore, such axon terminals bursting may participate in the triggering of the synchronous, prolonged intracellular depolarization shifts which are observed in cortical neurons during epileptic events.

摘要

投射到慢性皮质癫痫病灶的丘脑皮质中继神经元的皮质内轴突终末,在自发性皮质癫痫样发作期间可能会产生高频动作电位爆发。在大部分被测试的神经元中,此类爆发在相应的表面发作开始之前有规律地发生。因此,此类轴突终末爆发可能参与触发在癫痫发作期间皮质神经元中观察到的同步、长时间的细胞内去极化转变。

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Antidromic activation of pyramidal tract neurons following topical penicillin application. A possible mechanism in the generation of paroxysmal events.局部应用青霉素后锥体束神经元的逆向激活。阵发性事件发生的一种可能机制。
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新皮质中表达小白蛋白的中间神经元的活动依赖性异位放电
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Synaptic contacts on axons in the cerebral cortex.大脑皮质轴突上的突触联系。
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