Polus Jennifer S, Kaptein Bart L, Vasarhelyi Edward M, Lanting Brent A, Teeter Matthew G
School of Biomedical Engineering, Faculty of Engineering, Western University, London, Ontario, Canada.
Department of Orthopaedics, Leiden University Medical Center, Leiden, The Netherlands.
J Orthop Res. 2025 Jan;43(1):192-199. doi: 10.1002/jor.25981. Epub 2024 Oct 1.
Though radiostereometric analysis (RSA) is the gold standard for migration tracking, computed tomography-based RSA (CT-RSA) does not require marker beads and is available for clinical adoption. This study investigated CT-RSA in comparison to RSA for assessing hip implant stability with inducible displacement (ID) examinations. Patients (n = 48) from a previous study returned to be re-examined for femoral stem stability with CT-RSA and RSA imaging. Implant migration since patients last follow-up was calculated as a measure of stability. ID was assessed between alternated leg rotation scans for CT-RSA and between supine and weight-bearing scans for RSA. Measurements from ID and double examinations were compared between CT-RSA and RSA. All stems were well-fixed with migration <0.2 mm/year. ID measurements were lower with CT-RSA than RSA for distal translation (mean difference = 0.122 mm, p < 0.0001), total translation (mean difference = 0.158 mm, p < 0.0001), and total rotation (mean difference = 0.449°, p < 0.0001). The ID and double exam were significantly different for total translation and total rotation for CT-RSA, and significantly different for medial, distal, and total translation, and total rotation for RSA. Precision ranged from 0.049 to 0.130 mm in translation and 0.061° to 0.220° in rotation for CT-RSA, and from 0.108 to 0.269 mm in translation and 0.151° to 0.670° in rotation for RSA. ID measurements from both CT-RSA and RSA were minimal, consistent for a cohort with well-fixed stems. CT-RSA demonstrated superior precision in all axes compared to RSA. Clinical Significance: Future work should explore the use of CT-RSA in patients with suspected loosening as a potential diagnostic tool.
尽管放射性立体测量分析(RSA)是评估植入物移位的金标准,但基于计算机断层扫描的RSA(CT-RSA)不需要标记珠,可用于临床。本研究比较了CT-RSA和RSA在通过诱导性移位(ID)检查评估髋关节植入物稳定性方面的差异。之前一项研究中的患者(n = 48)返回进行CT-RSA和RSA成像,以重新检查股骨柄稳定性。计算自患者上次随访以来的植入物移位情况,作为稳定性的一项指标。对于CT-RSA,在交替腿部旋转扫描之间评估ID;对于RSA,在仰卧位和负重扫描之间评估ID。比较CT-RSA和RSA在ID及双重检查中的测量结果。所有股骨柄固定良好,移位<0.2毫米/年。在远端平移(平均差异 = 0.122毫米,p < 0.0001)、总平移(平均差异 = 0.158毫米,p < 0.0001)和总旋转(平均差异 = 0.449°,p < 0.0001)方面,CT-RSA的ID测量值低于RSA。对于CT-RSA,ID和双重检查在总平移和总旋转方面存在显著差异;对于RSA,在内侧、远端和总平移以及总旋转方面存在显著差异。CT-RSA的平移精度范围为0.049至0.130毫米,旋转精度范围为0.061°至0.220°;RSA的平移精度范围为0.108至0.269毫米,旋转精度范围为0.151°至0.670°。CT-RSA和RSA 的ID测量值都很小,这与一组股骨柄固定良好的队列情况一致。与RSA相比,CT-RSA在所有轴向上都显示出更高的精度。临床意义:未来的研究应探索将CT-RSA用于疑似松动患者,作为一种潜在的诊断工具。