Raab W P, Tronnier H, Wiskemann A
Dermatologica. 1985;171(5):371-3. doi: 10.1159/000249456.
A new combination of beta-carotene (25 mg) and canthaxanthin (35 mg) was clinically investigated in 74 patients with various photodermatoses and 111 patients with pigmentation disorders. The photoprotective action of this combination was ascertained in clinical experiments. Serum levels were determined in 20 patients; the absence of increased retinol levels could be confirmed. In 23 patients, ophthalmological controls did not reveal any abnormalities. In 65 of the 74 patients with photodermatoses, a satisfactory protective action was recorded. 85 of the 111 patients with depigmentations and hyperpigmentations experienced a marked decrease of the disturbing contrast between their lesions and the surrounding skin.
对74例患有各种光皮肤病的患者和111例色素沉着紊乱患者进行了β-胡萝卜素（25毫克）和角黄素（35毫克）新组合的临床研究。在临床实验中确定了该组合的光保护作用。测定了20例患者的血清水平；可以确认视黄醇水平没有升高。在23例患者中，眼科检查未发现任何异常。在74例光皮肤病患者中的65例中，记录到了令人满意的保护作用。111例色素脱失和色素沉着患者中的85例，其皮损与周围皮肤之间令人烦恼的色差明显降低。
