Inui Y, Miwa S
Gen Comp Endocrinol. 1985 Dec;60(3):450-4. doi: 10.1016/0016-6480(85)90080-2.
The role of thyroid hormone in flounder metamorphosis was studied by use of thyroxine and the antithyroidal agent, thiourea (TU). T4 stimulated metamorphosis of pelagic larvae, producing miniatures of naturally metamorphosed benthic juveniles. In contrast, TU induced metamorphic stasis, resulting in giant pelagic larvae. These results indicate that the thyroid plays a role in flounder metamorphosis comparable to its well-known developmental role in amphibian metamorphosis.
通过使用甲状腺素和抗甲状腺药物硫脲(TU),研究了甲状腺激素在比目鱼变态中的作用。T4刺激了浮游幼虫的变态,产生了自然变态的底栖幼鱼的微型模型。相比之下,TU诱导了变态停滞,导致出现巨大的浮游幼虫。这些结果表明,甲状腺在比目鱼变态中所起的作用与其在两栖动物变态中众所周知的发育作用相当。