Vora Ariana, Kennedy-Spaien Eve, Gray Sarah, Estudillo-Guerra Anayali Maria, Phillips Gabriele, Mesia-Toledo Ines, Glenn Mel, Chin Bridget S, Morales-Quezada Leon
Spaulding Integrative Health Initiative, Spaulding Rehabilitation Hospital, Boston, MA, United States.
Department of Physical Medicine & Rehabilitation, Spaulding Rehabilitation Hospital, Boston, MA, United States.
Front Psychol. 2024 Sep 13;15:1448117. doi: 10.3389/fpsyg.2024.1448117. eCollection 2024.
describes helplessness, rumination, and magnification of a pain experience. High pain catastrophizing is an independent risk factor for disability, pain severity, inadequate treatment response, chronicity, and opioid misuse. Interdisciplinary pain programs (IPPs) are beneficial and cost-effective for individuals with chronic pain, but their functional impact on individuals with high pain catastrophizing is not well established. The emerging field of placebo studies suggests that patient-provider relationships, positive treatment expectations, and sociobiologically informed care trigger physiological responses that may enhance therapeutic interventions.
In this retrospective observational cohort study, we compared admission and discharge data for 428 adults with high-impact chronic pain (mean 8.5 years) who completed the Spaulding-Medford Functional Restoration Program (FRP). The interdisciplinary FRP team of physiatrists, behavioral health clinicians, physical therapists, and occupational therapists specializes in evidenced-based conventional rehabilitation, integrative health, and pain psychoeducation via enriched therapeutic encounters, fostering collaboration, validation, trust, self-efficacy, and positive expectations. Clinical outcome measures included the Canadian Occupational Performance Measure (COPM) assessing functional performance (COPM-PS) and satisfaction with function (COPM-SS), the Pain Numeric Rating Scale (NRS), the Pain Catastrophizing Scale (PCS), and the Patient Health Questionnaire-9 (PHQ-9).
FRP participants with clinically elevated catastrophizing at baseline (PCS ≥30, mean PCS 39) achieved statistically significant improvements in function (mean delta -2.09, CHI2 = 15.56, < 0.001), satisfaction with function (COPM-SS mean delta -2.50, CHI2 = 7.42, = 0.007), pain (NRS mean delta 2.7), mood (PHQ-9 mean delta 1.87, = 0.002), and catastrophizing (PCS mean delta 4.16, < 0.001). Subgroup analysis revealed racial disparities in pain scores, and exploratory analysis showed a trend toward reducing opiate consumption.
Despite the known association of adverse outcomes with high catastrophizing, FRP participation was associated with increased productive engagement, reduced pain, reduced maladaptive thought processes, and improved mood. Although causation and efficacy cannot be established from a retrospective design, this is the first study to identify functional improvement in patients with high-impact chronic pain and clinically relevant high pain catastrophizing who participate in an IPP combining conventional and complementary rehabilitation with psychoeducation. These enriched therapeutic encounters may enhance the treatment process by promoting trust, empathy, collaboration, and beneficial reframing of patients' experiences, expectations, and goals.
描述了无助感、反复思考以及对疼痛体验的放大。高疼痛灾难化是导致残疾、疼痛严重程度、治疗反应不足、慢性化和阿片类药物滥用的独立风险因素。跨学科疼痛项目(IPPs)对慢性疼痛患者有益且具有成本效益,但其对高疼痛灾难化个体的功能影响尚不明确。安慰剂研究的新兴领域表明,医患关系、积极的治疗期望以及基于社会生物学的护理会引发生理反应,这可能会增强治疗干预效果。
在这项回顾性观察队列研究中,我们比较了428名患有高影响慢性疼痛(平均8.5年)并完成斯波尔丁 - 梅德福德功能恢复项目(FRP)的成年人的入院和出院数据。由物理治疗师、行为健康临床医生、物理治疗师和职业治疗师组成的跨学科FRP团队,通过丰富的治疗接触,专注于循证传统康复、综合健康和疼痛心理教育,促进合作、认可、信任、自我效能感和积极期望。临床结局指标包括评估功能表现的加拿大职业表现测量量表(COPM)(COPM - PS)和功能满意度(COPM - SS)、疼痛数字评定量表(NRS)、疼痛灾难化量表(PCS)以及患者健康问卷 - 9(PHQ - 9)。
基线时临床灾难化程度升高(PCS≥30,平均PCS为39)的FRP参与者在功能(平均变化值 - 2.09,CHI2 = 15.56,P < 0.001)、功能满意度(COPM - SS平均变化值 - 2.50,CHI2 = 7.42,P = 0.007)、疼痛(NRS平均变化值2.7)、情绪(PHQ - 9平均变化值1.87,P = 0.002)和灾难化程度(PCS平均变化值4.16,P < 0.001)方面取得了具有统计学意义的改善。亚组分析揭示了疼痛评分中的种族差异,探索性分析显示有减少阿片类药物消费的趋势。
尽管已知不良后果与高灾难化有关,但参与FRP与生产性参与增加、疼痛减轻、适应不良思维过程减少以及情绪改善有关。虽然回顾性设计无法确定因果关系和疗效,但这是第一项确定参与结合传统与补充康复及心理教育的IPPs的高影响慢性疼痛且临床相关高疼痛灾难化患者功能改善的研究。这些丰富的治疗接触可能通过促进信任、同理心、合作以及对患者经历、期望和目标的有益重新构建来增强治疗过程。