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猪小肠黏膜下层生物材料移植物修复幼猫先天性胸腹疝。

Porcine small intestinal submucosa biomaterial graft for repair of a congenital pleuroperitoneal hernia in a kitten.

机构信息

Surgery Service, Veterinary Emergency Clinic and Referral Centre (Freitas) and Department of Companion Animals (Hoddinott), Atlantic Veterinary College, University of Prince Edward Island, 550 University Avenue, Charlottetown, Prince Edward Island C1A 4P3.

出版信息

Can Vet J. 2024 Oct;65(10):999-1005.

Abstract

In this case, porcine small intestinal submucosa (pSIS) was used to repair a large congenital diaphragmatic hernia in a kitten. The pSIS was moistened in saline, folded in half, and sutured to the remnant of the right hemidiaphragm. The animal was determined to be doing well clinically and radiographically 12 wk after procedure. At 8.5 mo of age, the kitten was spayed, and the diaphragm was inspected, revealing a thin, semitransparent membrane at the central region of the previous pSIS graft. Serial thoracic radiographs may be an effective way to reach a diagnosis of a diaphragmatic hernia if not clearly identifiable on initial radiographs. Surgeons should be prepared to use alternative techniques to close large diaphragmatic defects. Porcine SIS was demonstrated to be a strong, easy-to-use, readily available, and effective technique to close a large defect in the diaphragm with excellent results in the short and medium terms. When hernia repair is employed in juvenile animals, reassessment of the diaphragmatic repair should be considered if future abdominal surgeries, such as ovariohysterectomies, are necessary. A functional 8-ply pSIS should be considered in cats and dogs as it has a lower complication and graft failure rate. Key clinical message: When serial radiographs fail to diagnose a diaphragmatic hernia when one is highly suspected, other modalities, such as ultrasonography or other contrast modalities, should be considered. A functional 8-ply pSIS should be considered to reconstruct the diaphragm, particularly in growing animals, as it is an effective graft with low complication and graft failure rates.

摘要

在这种情况下,使用猪小肠黏膜下层(pSIS)修复了一只小猫的先天性膈疝。将 pSIS 用生理盐水浸湿,对折后缝合到右膈肌残端上。术后 12 周,动物在临床和放射学上均被确定恢复良好。在 8.5 月龄时,对小猫进行了绝育手术,并检查了膈肌,发现前 pSIS 移植物的中央区域有一层薄而半透明的膜。如果初次放射学检查不能明确诊断膈疝,连续的胸部 X 线片可能是一种有效的诊断方法。如果膈疝较大,外科医生应准备使用替代技术来关闭。猪 SIS 被证明是一种强大、易于使用、易于获得且有效的技术,可在短期内和中期内闭合膈疝的大缺陷,并取得良好效果。如果未来需要进行腹部手术,如卵巢子宫切除术,在幼年动物中进行疝修补术时,应考虑重新评估膈疝的修复情况。对于猫和狗,应考虑使用功能性 8 层 pSIS,因为它的并发症和移植物失败率较低。关键临床信息:如果高度怀疑存在膈疝但连续的放射学检查未能诊断出,则应考虑其他方式,如超声或其他对比方式。对于生长中的动物,应考虑使用功能性 8 层 pSIS 来重建膈肌,因为它是一种有效的移植物,并发症和移植物失败率较低。

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本文引用的文献

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Reconstruction of a large diaphragmatic defect in a kitten using small intestinal submucosa (SIS).
J Feline Med Surg. 2009 Dec;11(12):1019-22. doi: 10.1016/j.jfms.2009.06.003. Epub 2009 Aug 22.
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