Chukwu C C
Int J Zoonoses. 1985 Jun;12(2):120-5.
The serum agglutinin titres of six heifers experimentally inoculated with live Br. abortus strain 45/20 were similar to those produced in six bullocks inoculated with virulent Br. abortus strain 544. However, the agglutinin response appeared slowly and disappeared earlier in the heifers than in the bullocks. It is concluded that Br. abortus strain 45/20 is an unstable strain, could revert to the smooth form and become highly agglutinogenic in non-pregnant heifers. The significance of using an unstable rough strain of Br. abortus vaccine in the diagnosis of bovine brucellosis is briefly discussed.
六头经实验接种活布鲁氏菌45/20菌株的小母牛血清凝集素效价，与六头接种强毒布鲁氏菌544菌株的公牛所产生的血清凝集素效价相似。然而，小母牛的凝集素反应出现得较慢，且比公牛消失得更早。得出的结论是，布鲁氏菌45/20菌株是一种不稳定菌株，可能会回复到光滑型，并在未怀孕的小母牛中变得高度凝集原性。文中简要讨论了使用不稳定的粗糙型布鲁氏菌疫苗株在牛布鲁氏菌病诊断中的意义。
