Gomes Samira Vasconcelos, Nunes-Dos-Santos Danila Lorena, Branco-De-Almeida Luciana Salles, Benatti Bruno Braga, Rodrigues Vandilson
Universidade Federal do Maranhão, Departamento de Odontologia, São Luís, Brasil.
Universidade Federal do Maranhão, Hospital Universitário, São Luís, Brasil.
J Appl Oral Sci. 2024 Sep 30;32:e20240206. doi: 10.1590/1678-7757-2024-0206. eCollection 2024.
This study sought to investigate the relationship between clinical response to nonsurgical periodontal therapy (NSPT) and serum changes in leukocyte count, fasting blood glucose, hemoglobin, hematocrit, creatinine, and uric acid in kidney transplant recipients (KTR).
A prospective study was performed on 20 KTRs. Periodontal and serum data were collected before and 90 days after NSPT, and delta values (Δ = after NSPT - before) were calculated. Periodontal assessment included periodontal probing depth (PPD), clinical attachment level (CAL), and bleeding on probing (BOP). Patients were classified based on the presence of periodontitis and then categorized into stages.
Patients showed a reduction in the percentage of sites with PPD≥3mm, PPD≥4 mm and BOP, after NSPT. There was a direct correlation between the deltas of leukocyte count and CAL ≥3 mm (r=0.645, P=0.002) and BOP (r=0.663, P=0.001), and the deltas of uric acid and CAL ≥3 mm (r=0.562, P=0.010).
A good clinical response to NSPT may affect the reduction of serum levels of leukocyte count and uric acid, suggesting a beneficial effect on systemic health in KTR.
本研究旨在调查肾移植受者（KTR）对非手术牙周治疗（NSPT）的临床反应与白细胞计数、空腹血糖、血红蛋白、血细胞比容、肌酐和尿酸的血清变化之间的关系。
对20名KTR进行了一项前瞻性研究。在NSPT前和NSPT后90天收集牙周和血清数据，并计算差值（Δ = NSPT后 - NSPT前）。牙周评估包括牙周探诊深度（PPD）、临床附着水平（CAL）和探诊出血（BOP）。根据牙周炎的存在对患者进行分类，然后分为不同阶段。
NSPT后，患者PPD≥3mm、PPD≥4mm和BOP部位的百分比降低。白细胞计数差值与CAL≥3mm（r = 0.645，P = 0.002）和BOP（r = 0.663，P = 0.001）之间存在直接相关性，尿酸差值与CAL≥3mm（r = 0.562，P = 0.010）之间存在直接相关性。
对NSPT良好的临床反应可能会影响白细胞计数和尿酸血清水平的降低，表明对KTR的全身健康有有益影响。
