甲状腺激素的皮质作用：探索与代谢的交叉路口。

Cortical actions of thyroid hormone: An exploration and metabolism crossroad.

机构信息

NeurObesity Group, Department of Physiology, CiMUS, University of Santiago de Compostela, Santiago de Compostela 15782, Spain; CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Santiago de Compostela 15706, Spain.

出版信息

Cell Metab. 2024 Oct 1;36(10):2170-2172. doi: 10.1016/j.cmet.2024.09.004.

DOI:10.1016/j.cmet.2024.09.004

PMID:39357508

Abstract

Classically, the central actions of thyroid hormones (THs) on metabolism occur within the hypothalamus. A recent article published in Cell by Sabatini and colleagues demonstrates that TH modulates cerebral cortical circuits of male mice, which might integrate exploratory behavior and whole-body metabolism.

摘要

经典理论认为，甲状腺激素（THs）对代谢的中枢作用发生在下丘脑。Sabatini 及其同事最近在《细胞》杂志上发表的一篇文章表明，TH 调节雄性小鼠大脑皮质回路，这可能整合了探索行为和全身代谢。