NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Trends Biochem Sci. 2024 Nov;49(11):933-935. doi: 10.1016/j.tibs.2024.09.005. Epub 2024 Oct 1.
A recent report by Yun et al. describes the detection of RAS dimers using intact mass spectrometry and investigates the role that membrane lipids, nucleotide state, and binding partners have in their formation.
云等人最近的一份报告描述了使用完整质谱法检测 RAS 二聚体,并研究了膜脂、核苷酸状态和结合伴侣在其形成中的作用。