Dulay Mansimran Singh, Ahmed Raheel, Child Nick, Arnold Ahran, Tanner Mark
Department of Cardiology, Royal Brompton and Harefield Hospitals, Guy's and St Thomas NHS Foundation Trust, London, UK.
King's College London, London, UK.
Eur Heart J Case Rep. 2024 Sep 24;8(10):ytae494. doi: 10.1093/ehjcr/ytae494. eCollection 2024 Oct.
There is emerging evidence for the potential utility of left bundle branch area pacing (LBBAP), as an alternative to conventional cardiac resynchronization therapy (CRT). The utility of right ventriculography by way of power injector to facilitate lead placement has not yet been reported in the literature.
A 79-year-old female, with a background of poorly rate-controlled atrial fibrillation, presented with worsening dyspnoea. She had recently undergone single-chamber pacemaker insertion prior to an atrioventricular nodal (AVN) ablation, owing to failure in achieving successful CRT coronary sinus lead placement. She had clinical evidence of volume overload, and her electrocardiogram demonstrated right ventricular pacing. Echocardiography demonstrated left ventricular (LV) impairment, with an ejection fraction (EF) of 35%, and severe functional mitral regurgitation (MR). Her diagnosis was overall consistent with pacing-induced cardiomyopathy (PIC). In this patient, the use of right ventriculography, using power-injector-delivered contrast, successfully facilitated placement of an LBBAP lead, with confirmation of good threshold and sensing parameters. Following an upgrade to conduction system pacing, the patient recovered well. On recent follow-up, repeat echocardiography (24 months post initial presentation) demonstrated improved LV function (EF 45% from 35%) and only mild-to-moderate MR.
In conclusion, we demonstrate the utility of right ventriculography to facilitate placement of an LBBAP lead, successfully treating a patient who developed PIC from chronic right ventricular pacing following AVN ablation.
越来越多的证据表明左束支区域起搏(LBBAP)作为传统心脏再同步治疗(CRT)的替代方法具有潜在效用。通过动力注射器进行右心室造影以辅助导线置入的效用尚未见文献报道。
一名79岁女性,有心率控制不佳的心房颤动病史,因呼吸困难加重就诊。由于未能成功置入CRT冠状窦导线,她最近在房室结(AVN)消融术前植入了单腔起搏器。她有容量超负荷的临床证据,心电图显示右心室起搏。超声心动图显示左心室(LV)功能受损,射血分数(EF)为35%,并有严重功能性二尖瓣反流(MR)。她的诊断总体上符合起搏诱导的心肌病(PIC)。在该患者中,使用动力注射器注入造影剂进行右心室造影,成功辅助置入了LBBAP导线,并确认阈值和感知参数良好。升级为传导系统起搏后,患者恢复良好。在最近的随访中,重复超声心动图检查(初次就诊后24个月)显示左心室功能改善(EF从35%提高到45%),仅存在轻度至中度MR。
总之,我们证明了右心室造影辅助LBBAP导线置入的效用,成功治疗了一名因AVN消融术后慢性右心室起搏而发生PIC的患者。