Kendrick K M, Dixson A F
Neuroendocrinology. 1985 Dec;41(6):449-53. doi: 10.1159/000124218.
Luteinizing hormone releasing hormone (LHRH) administered to ovariectomized marmosets treated with a low dose of 17 beta-oestradiol significantly enhanced proceptivity within 2 h. Without oestradiol priming LHRH treatment did not produce this effect. The dose of LHRH given did not significantly alter plasma levels of cortisol or progesterone. The behavioural effect of this treatment is therefore likely to have been mediated via a direct central action rather than indirectly through stimulating adrenocortical steroid secretion. These results provide the first demonstration that LHRH can potentiate the proceptive behaviour of a female primate.
给用低剂量17β-雌二醇治疗的去卵巢狨猴注射促黄体生成素释放激素(LHRH),在2小时内显著增强了接受性。没有雌二醇预处理,LHRH治疗不会产生这种效果。所给予的LHRH剂量并未显著改变皮质醇或孕酮的血浆水平。因此,这种治疗的行为效应可能是通过直接的中枢作用介导的,而不是通过刺激肾上腺皮质类固醇分泌间接介导的。这些结果首次证明LHRH可以增强雌性灵长类动物的接受性行为。