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Cancer Med. 2023 Mar;12(5):6129-6138. doi: 10.1002/cam4.5345. Epub 2022 Oct 13.
2
Parent-initiated posthumous-assisted reproduction revisited in light of the interest in genetic origins.从遗传起源的角度重新审视由父母发起的死后辅助生殖。
J Med Ethics. 2023 May;49(5):357-360. doi: 10.1136/medethics-2022-108204. Epub 2022 Jun 20.
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Posthumous assisted reproduction policies among a cohort of United States' in vitro fertilization clinics.美国一组体外受精诊所的死后辅助生殖政策。
F S Rep. 2020 Sep 2;1(2):66-70. doi: 10.1016/j.xfre.2020.06.005. eCollection 2020 Sep.
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Anticipatory grief and impaired problem solving among surrogate decision makers of critically ill patients: A cross-sectional study.危重患者代理人的预期性悲伤和解决问题能力受损:一项横断面研究。
Intensive Crit Care Nurs. 2018 Dec;49:1-5. doi: 10.1016/j.iccn.2018.07.006. Epub 2018 Jul 26.
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Fertility Preservation in Patients With Cancer: ASCO Clinical Practice Guideline Update.癌症患者的生育力保存:ASCO 临床实践指南更新。
J Clin Oncol. 2018 Jul 1;36(19):1994-2001. doi: 10.1200/JCO.2018.78.1914. Epub 2018 Apr 5.
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Patient Educ Couns. 2016 Nov;99(11):1907-1910. doi: 10.1016/j.pec.2016.05.013. Epub 2016 May 17.
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Posthumous collection and use of reproductive tissue: a committee opinion.死后采集和使用生殖组织:委员会意见。
Fertil Steril. 2013 Jun;99(7):1842-5. doi: 10.1016/j.fertnstert.2013.02.022. Epub 2013 Mar 5.
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Fertility preservation in cancer patients: ethical considerations.癌症患者的生育力保存:伦理考量
Adv Exp Med Biol. 2012;732:187-96. doi: 10.1007/978-94-007-2492-1_15.
9
The dual process model of coping with bereavement: a decade on.应对丧亲的双重过程模型:十年回顾。
Omega (Westport). 2010;61(4):273-89. doi: 10.2190/OM.61.4.b.
10
ESHRE Task Force on Ethics and Law 11: Posthumous assisted reproduction.欧洲人类生殖与胚胎学会伦理与法律特别工作组11:死后辅助生殖。
Hum Reprod. 2006 Dec;21(12):3050-3. doi: 10.1093/humrep/del287. Epub 2006 Aug 21.

悲伤情境下癌症预后不良的青少年和年轻人死后辅助生殖的伦理与心理考量

Ethical and Psychological Considerations for Posthumous-Assisted Reproduction for Adolescents and Young Adults With Poor Cancer Prognosis in the Context of Grief.

作者信息

Parchem Benjamin, Rider G Nic, Quinn Gwendolyn P

机构信息

Institute for Sexual and Gender Health, Department of Family Medicine and Community Health, University of Minnesota Medical School.

Department of Obstetrics and Gynecology, New York University Grossman School of Medicine.

出版信息

Clin Pract Pediatr Psychol. 2024 Sep;12(3):358-365. doi: 10.1037/cpp0000502. Epub 2024 Mar 14.

DOI:10.1037/cpp0000502
PMID:39359488
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11444213/
Abstract

OBJECTIVE

Families or loved ones of adolescents and young adults (AYA) with a poor cancer prognosis who preserved fertility and did not survive treatment may choose to pursue posthumous assisted reproduction (PAR; i.e., use of preserved reproductive material for future family-building attempts). Decisions about PAR may be occurring in the context of grief and bereavement, which is associated with ethical and psychological considerations because grief can complicate a person's capacity for informed decision-making.

METHODS

Through the use of a five-step ethical decision-making model, the American Psychological Association's Ethical Principles of Psychologists and Code of Conduct, and a blended case example, the ethical and psychological considerations for families of AYA with poor prognosis who pursue PAR is discussed with an ethical analysis.

RESULTS

Ethical and psychological considerations included assessing the potential for harm to involved parties, navigating PAR decision-making with responsibility and honesty, examining the accessibility of PAR, and considering informed consent/assent and autonomy.

CONCLUSIONS

Clinical recommendations for supporting families and loved ones exploring PAR in the context of grief were discussed, with considerations for improving clinicians' comfort and competence with PAR, incorporating grief into informed consent conversations, standardizing conversations about PAR, and promoting an interdisciplinary approach to PAR-related decisions.

摘要

目的

癌症预后较差的青少年及年轻成人(AYA)在保留生育能力但治疗后未存活的情况下,其家人或爱人可能会选择进行死后辅助生殖(PAR,即使用保存的生殖材料进行未来组建家庭的尝试)。关于PAR的决策可能是在悲痛和丧亲之痛的背景下做出的,这涉及伦理和心理方面的考量,因为悲痛会使一个人做出明智决策的能力变得复杂。

方法

通过使用五步伦理决策模型、美国心理学会的《心理学家伦理原则与行为准则》以及一个混合案例,对预后较差的AYA家庭进行PAR时的伦理和心理考量进行探讨并进行伦理分析。

结果

伦理和心理考量包括评估对相关方造成伤害的可能性、以负责和诚实的态度进行PAR决策、审视PAR的可及性,以及考虑知情同意/赞同和自主性。

结论

讨论了在悲痛背景下支持探索PAR的家庭和爱人的临床建议,包括提高临床医生对PAR的舒适度和能力、将悲痛纳入知情同意谈话、规范关于PAR的谈话,以及促进对PAR相关决策采取跨学科方法。