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精神分裂症中的吞咽困难:病理机制及治疗建议

Dysphagia in schizophrenia: pathological mechanisms and treatment recommendations.

作者信息

Wang Jiahui, Gao Caifeng, Fu Cuiyuan, Li Kun

机构信息

Shandong Daizhuang Hospital, Jining, Shandong, China.

出版信息

Front Psychiatry. 2024 Sep 17;15:1448623. doi: 10.3389/fpsyt.2024.1448623. eCollection 2024.

DOI:10.3389/fpsyt.2024.1448623
PMID:39359857
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11445750/
Abstract

Schizophrenia is a chronic, severe, and disabling mental disorder that significantly impacts individuals' lives. Long-term treatment with antipsychotic drugs, coupled with the complications of the disease itself, increases the risk of dysphagia in patients. These disorders further heighten the likelihood of choking and asphyxia death among this population. This project aims to comprehensively review the pathological mechanisms behind dysphagia in schizophrenia, alongside proposing early screening and evaluation methods. It also suggests treatment recommendations to mitigate the risks and complications associated with dysphagia in these patients.

摘要

精神分裂症是一种慢性、严重且致残的精神障碍,会对个人生活产生重大影响。抗精神病药物的长期治疗,再加上疾病本身的并发症,增加了患者吞咽困难的风险。这些病症进一步提高了该人群窒息和窒息死亡的可能性。本项目旨在全面综述精神分裂症患者吞咽困难背后的病理机制,同时提出早期筛查和评估方法。它还提出了治疗建议,以降低这些患者吞咽困难相关的风险和并发症。

相似文献

1
Dysphagia in schizophrenia: pathological mechanisms and treatment recommendations.精神分裂症中的吞咽困难:病理机制及治疗建议
Front Psychiatry. 2024 Sep 17;15:1448623. doi: 10.3389/fpsyt.2024.1448623. eCollection 2024.
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Ment Health Clin. 2018 Mar 23;7(2):56-64. doi: 10.9740/mhc.2017.03.056. eCollection 2017 Mar.
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Validation of a Geriatric Bedside Swallowing Screen (GEBS): Protocol of a Prospective Cohort Study.老年床边吞咽筛查(GEBS)的验证:一项前瞻性队列研究方案
JMIR Res Protoc. 2023 Aug 11;12:e46252. doi: 10.2196/46252.

本文引用的文献

1
Antipsychotic-induced acute laryngeal dystonia: A systematic review of case reports.抗精神病药引起的急性喉痉挛:病例报告的系统评价。
Schizophr Res. 2024 Feb;264:248-262. doi: 10.1016/j.schres.2023.12.032. Epub 2024 Jan 6.
2
Observational study of effects of pharyngeal stimulation by carbonated solution on repetitive voluntary swallowing in humans.观察性研究:碳酸溶液对人体重复自主吞咽的咽部刺激作用。
Medicine (Baltimore). 2023 Aug 25;102(34):e34889. doi: 10.1097/MD.0000000000034889.
3
A systematic chart review of pharmacological interventions in patients with clozapine-induced hypersalivation.
氯氮平致流涎患者药物干预的系统图表回顾。
Schizophr Res. 2024 Jun;268:138-144. doi: 10.1016/j.schres.2023.08.004. Epub 2023 Aug 17.
4
Dysphagia screening post-stroke: systematic review.中风后吞咽困难筛查:系统评价
BMJ Support Palliat Care. 2024 Jan 8;13(e3):e641-e650. doi: 10.1136/spcare-2022-004144.
5
Unraveling the pathophysiology of schizophrenia: insights from structural magnetic resonance imaging studies.揭示精神分裂症的病理生理学:来自结构磁共振成像研究的见解。
Front Psychiatry. 2023 May 19;14:1188603. doi: 10.3389/fpsyt.2023.1188603. eCollection 2023.
6
Efficacy of Transcranial Direct Current Stimulation Combined with Conventional Swallowing Rehabilitation Training on Post-stroke Dysphagia.经颅直流电刺激联合常规吞咽康复训练治疗脑卒中后吞咽障碍的疗效。
Dysphagia. 2023 Dec;38(6):1537-1545. doi: 10.1007/s00455-023-10581-2. Epub 2023 May 5.
7
Large-scale analysis of structural brain asymmetries in schizophrenia via the ENIGMA consortium.通过 ENIGMA 联盟对精神分裂症结构大脑不对称性进行大规模分析。
Proc Natl Acad Sci U S A. 2023 Apr 4;120(14):e2213880120. doi: 10.1073/pnas.2213880120. Epub 2023 Mar 28.
8
Diagnostic Accuracy of the Eating Assessment Tool-10 (EAT-10) in Screening Dysphagia: A Systematic Review and Meta-Analysis.《进食评估工具-10(EAT-10)在吞咽障碍筛查中的诊断准确性:系统评价和荟萃分析》。
Dysphagia. 2023 Feb;38(1):145-158. doi: 10.1007/s00455-022-10486-6. Epub 2022 Jul 18.
9
Cognitive impairment in people with schizophrenia: an umbrella review.精神分裂症患者的认知障碍:伞式综述。
Eur Arch Psychiatry Clin Neurosci. 2022 Oct;272(7):1139-1155. doi: 10.1007/s00406-022-01416-6. Epub 2022 May 28.
10
Prevalence of dysphagia and risk of pneumonia and mortality in acute stroke patients: a meta-analysis.急性脑卒中患者吞咽困难的发生率、肺炎风险和死亡率的 Meta 分析。
BMC Geriatr. 2022 May 13;22(1):420. doi: 10.1186/s12877-022-02960-5.