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[一种新型快速药敏试验方法——Rapid-ATB系统的评估。与琼脂稀释参考方法及标准药敏试验的比较]

[Evaluation of a new rapid antibiogram method, the Rapid-ATB system. Comparison with the agar dilution reference method and the standard antibiogram].

作者信息

Le Noc P, Gayral J P, Robert J

出版信息

Pathol Biol (Paris). 1985 Nov;33(9):906-10.

PMID:3936008
Abstract

Results given by Rapid-ATB, a new automated system for the four hour susceptibility testing of bacteria were compared in this study to results given by agar dilution test and disc agar diffusion test. For 100 Enterobacteriaceae strains tested against ten antibiotics, overall agreement between agar dilution test and Rapid-ATB was 99.4%. 6 major discordances concerning especially chloramphenicol were only detected in 1 000 realized susceptibility tests. Overall agreement between agar dilution test and disc agar diffusion test was 96.7%. Eighteen major discordances concerning alike chloramphenicol, but also doxycycline and nalidixic acid, and fifteen minor discordances were detected in this comparison. These results prove the high reliability of this new system which give results more precise than these of disc agar diffusion test.

摘要

在本研究中,对一种用于细菌四小时药敏试验的新型自动化系统Rapid-ATB给出的结果,与琼脂稀释试验和纸片琼脂扩散试验给出的结果进行了比较。对100株肠杆菌科细菌针对十种抗生素进行测试,琼脂稀释试验和Rapid-ATB之间的总体一致性为99.4%。在1000次药敏试验中,仅检测到6例主要不一致情况,尤其涉及氯霉素。琼脂稀释试验和纸片琼脂扩散试验之间的总体一致性为96.7%。在该比较中,检测到18例主要不一致情况,同样涉及氯霉素,还有强力霉素和萘啶酸,以及15例次要不一致情况。这些结果证明了这种新系统的高可靠性,其给出的结果比纸片琼脂扩散试验的结果更精确。

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