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肠道健康的关键:食品添加剂综述与展望

The key to intestinal health: a review and perspective on food additives.

作者信息

Wang Haitao, Bai Junyi, Miao Pengyu, Wei Yu, Chen Xiaochao, Lan Haibo, Qing Yong, Zhao Meizhu, Li Yanyu, Tang Rui, Yang Xiangdong

机构信息

The School of Clinical Medical Sciences, Southwest Medical University, Luzhou, Sichuan, China.

Chengdu Anorectal Hospital, Chengdu, Sichuan, China.

出版信息

Front Nutr. 2024 Sep 18;11:1420358. doi: 10.3389/fnut.2024.1420358. eCollection 2024.

Abstract

In this review, we explore the effects of food additives on intestinal health. Food additives, such as preservatives, antioxidants and colorants, are widely used to improve food quality and extend shelf life. However, their effects on intestinal microecology May pose health risks. Starting from the basic functions of food additives and the importance of intestinal microecology, we analyze in detail how additives affect the diversity of intestinal flora, oxidative stress and immune responses. Additionally, we examine the association between food additives and intestinal disorders, including inflammatory bowel disease and irritable bowel syndrome, and how the timing, dosage, and individual differences affect the body's response to additives. We also assess the safety and regulatory policies of food additives and explore the potential of natural additives. Finally, we propose future research directions, emphasizing the refinement of risk assessment methods and the creation of safer, innovative additives.

摘要

在本综述中,我们探讨食品添加剂对肠道健康的影响。食品添加剂,如防腐剂、抗氧化剂和色素,被广泛用于改善食品质量和延长保质期。然而,它们对肠道微生态的影响可能会带来健康风险。从食品添加剂的基本功能和肠道微生态的重要性出发,我们详细分析了添加剂如何影响肠道菌群的多样性、氧化应激和免疫反应。此外,我们研究了食品添加剂与肠道疾病(包括炎症性肠病和肠易激综合征)之间的关联,以及时间、剂量和个体差异如何影响身体对添加剂的反应。我们还评估了食品添加剂的安全性和监管政策,并探索天然添加剂的潜力。最后,我们提出了未来的研究方向,强调风险评估方法的完善以及开发更安全、创新的添加剂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0059/11444971/d80a5738bd72/fnut-11-1420358-g001.jpg

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