Department of Nutrition and Clinical Nutrition, Faculty of Veterinary Medicine, Zagazig University, Zagazig, 44511, Egypt.
Department of Pathology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, 44511, Egypt.
Environ Sci Pollut Res Int. 2018 Jan;25(2):1340-1349. doi: 10.1007/s11356-017-0578-x. Epub 2017 Oct 31.
The present study was conducted to investigate the effect of graded levels of dietary bentonite supplementation on growth performance, carcass traits, nutrient digestibility, and histopathology of certain organs in rabbits fed a diet naturally contaminated with aflatoxin. In total, 125 weanling New Zealand White male rabbits were randomly assigned to five treatment groups each of five replicates. Treatments were as follows: T1, basal diet with no aflatoxin and no additives (positive control diet, PCD); T2, basal diet naturally contaminated with 150 ppb aflatoxin and no additives (negative control diet, NCD); T3, NCD plus 0.5% Egyptian bentonite; T4, NCD plus 1% Egyptian bentonite; and T5, NCD plus 1% Egyptian bentonite. The experiment lasted for 8 weeks. Results showed a significant decrease (P < 0.05) in the body weight and the body weight gain in the NCD, while they were improved (P < 0.05) in groups fed diets supplemented with different levels of bentonite. The relative weight of the liver and kidneys were higher in the NCD, while the liver weight was relatively high in the group fed NCD supplemented with 0.5% bentonite, and it was not significant in other bentonite-supplemented groups. Bentonite supplementation improved the digestibility coefficients of various nutrients. Bentonite addition decreased the histopathological lesions in liver, kidney, and intestine caused by aflatoxin-infected diets. In conclusion, bentonite supplementation overcame the negative effect of aflatoxin, enhanced growth performance traits, decreased the relative weights of the liver and the kidney which are usually increased by aflatoxin, caused significant improvement in nutrients' digestibility, and decreased the histopathological lesions caused by aflatoxin-infected diets. The level of 2% bentonite is recommended for ameliorating the aflatoxin effects.
本研究旨在探讨不同水平饲粮膨润土对采食天然受黄曲霉毒素污染日粮家兔生长性能、胴体特性、养分消化率和某些器官组织病理学的影响。选用 125 只 21 日龄新西兰白兔随机分为 5 个处理组，每组 5 个重复，每个重复 5 只兔。处理如下：T1，无黄曲霉毒素和添加剂的基础日粮（阳性对照日粮，PCD）；T2，天然受 150 ppb 黄曲霉毒素污染的基础日粮（阴性对照日粮，NCD）；T3，NCD 基础日粮添加 0.5%埃及膨润土；T4，NCD 基础日粮添加 1%埃及膨润土；T5，NCD 基础日粮添加 1%埃及膨润土。试验期 8 周。结果表明，NCD 组兔体重和体重增重显著下降（P<0.05），而添加不同水平膨润土的日粮组则有所改善（P<0.05）。NCD 组兔肝、肾相对重较高，而添加 0.5%膨润土的 NCD 组兔肝重相对较高，其他添加膨润土组差异不显著。膨润土的添加提高了各种养分的消化率系数。膨润土的添加降低了黄曲霉毒素感染日粮引起的肝、肾和肠的组织病理学病变。综上所述，膨润土的添加克服了黄曲霉毒素的负面影响，提高了生长性能指标，降低了黄曲霉毒素通常会增加的肝、肾相对重，显著提高了养分消化率，并降低了黄曲霉毒素感染日粮引起的组织病理学病变。建议添加 2%膨润土来缓解黄曲霉毒素的影响。
