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资源有限国家的癌症护理:以约旦为例。

Cancer Care in Resource-Limited Countries: Jordan as an Example.

机构信息

Department of Internal Medicine, King Hussein Cancer Center, Amman, Jordan.

School of Medicine, The University of Jordan, Amman, Jordan.

出版信息

JCO Glob Oncol. 2024 Sep;10:e2400237. doi: 10.1200/GO.24.00237. Epub 2024 Oct 3.

DOI:10.1200/GO.24.00237
PMID:39361906
Abstract

Jordan, a lower- to middle-income country, is relatively small, but with rapidly growing population and a challenged economy. Cancer is a growing health care problem and currently ranked second, after cardiovascular diseases, as a cause of death. Jordan's national cancer registry continues to suffer from problems mostly related to long lag time in reporting, absence of outcome data, and accurate staging. The number of new patients with cancer diagnosed in Jordan is increasing at an expected, none disturbing rate, fueled by population growth, improving life expectancy, changing population structure that hosts more older population, high rate of obesity, smoking, and lack of adequate exercise. However, age-standardized rate for cancer incidence is significantly lower than Western societies, yet, mortality rate is higher. Despite efforts, cancer is still diagnosed at more advanced stages and at younger age. The Jordan breast cancer program represents a great example of opportunistic screening that led to significant downstaging of breast cancer. Efforts to evaluate the feasibility of screening programs for colorectal and lung cancers are underway. Tremendous efforts resulted in the execution of the largest clinical cancer genetics program in the region that helps identify patients and at-risk relatives for hereditary cancers. Low-resourced countries, including Jordan, will not be able to keep up with the rapidly increasing cost of cancer care. A better access to clinical trials and moving cancer care to ambulatory settings should offset some of this cost. A cancer control program that addresses all issues of cancer care from screening and early detection, through active cost-effective treatment that assures wider access to palliative care, hospice, and survivorship programs under an expanded universal health coverage, is an urgent national health priority.

摘要

约旦是一个中低收入国家,国土面积相对较小,但人口增长迅速,经济面临挑战。癌症是一个日益严重的医疗保健问题,目前是继心血管疾病之后的第二大死因。约旦国家癌症登记处仍存在诸多问题,主要与报告滞后时间长、缺乏结局数据和准确分期有关。在人口增长、预期寿命延长、人口结构老龄化程度加剧、肥胖率高、吸烟和缺乏足够运动等因素的推动下,约旦新诊断癌症患者的数量正在以可预期的、并不令人担忧的速度增加。然而,癌症发病率的年龄标准化率明显低于西方国家,但死亡率却更高。尽管已经做出了努力,但癌症的诊断仍然处于较晚期,且发病年龄更小。约旦乳腺癌项目是机会性筛查的一个很好的例子,这导致了乳腺癌分期的显著降低。目前正在努力评估结直肠癌和肺癌筛查计划的可行性。巨大的努力促成了该地区最大的临床癌症遗传学计划的实施,该计划有助于识别遗传性癌症患者和高危亲属。包括约旦在内的资源有限的国家将无法承担癌症治疗费用的快速增长。更好地获得临床试验和将癌症治疗转移到门诊环境应该可以抵消部分成本。一个涵盖了从筛查和早期发现到积极有效的治疗的癌症控制计划,确保更多人能够获得姑息治疗、临终关怀和生存计划,这是一项紧迫的国家卫生优先事项。

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