从非洲视角看遗传多样性的人类诱导多能干细胞系。
An African perspective on genetically diverse human induced pluripotent stem cell lines.
机构信息
Bioengineering and Integrated Genomics Group, Council for Scientific and Industrial Research, Pretoria, South Africa.
Department of Human Biology, University of Cape Town, Cape Town, South Africa.
出版信息
Nat Commun. 2024 Oct 3;15(1):8581. doi: 10.1038/s41467-024-52781-w.
Abstract
Human induced pluripotent stem cell-derived models are a well-established preclinical tool, with the ability to retain the genetics of the individual from which they are derived. Here we comment on the global representation and accessibility of such cellular tools from African population groups.
摘要
人类诱导多能干细胞衍生模型是一种成熟的临床前工具，能够保留其来源个体的遗传信息。在这里，我们评论了来自非洲人群的此类细胞工具的全球代表性和可及性。
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