Kunitomi Taro, Miyagami Taiju, Kiyose Yuji, Terukina Hiroyuki, Kawabata Ritsuko, Watanabe Yu, Yamamoto Yusuke, Naito Toshio
Department of Medicine, Faculty of Medicine, Juntendo University, Tokyo, JPN.
Department of General Medicine, Jyuntendo University Hospital, Tokyo, JPN.
Cureus. 2024 Sep 3;16(9):e68517. doi: 10.7759/cureus.68517. eCollection 2024 Sep.
Angioimmunoblastic T-cell lymphoma (AITL) is a rare and challenging subtype of T-cell lymphoma often presenting with skin rashes and difficult diagnostic features. Its presentation can mimic other conditions, complicating accurate diagnosis. This case shows AITL in a 74-year-old man initially presenting with anemia that mimicked pure red cell anemia caused by parvovirus B19. The patient exhibited direct Coombs-positive anemia and recurrent urticarial-like rashes, which were initially misleading. This case emphasizes the critical need for considering lymphoma in patients presenting with direct Coombs-positive anemia and recurrent urticarial-like rashes It underscores the importance of revisiting and thoroughly assessing medical histories to enable accurate diagnosis, even when initial presentations suggest alternative diagnoses. Early recognition and appropriate management of AITL are crucial for improving patient outcomes.
血管免疫母细胞性T细胞淋巴瘤（AITL）是一种罕见且具有挑战性的T细胞淋巴瘤亚型，常表现为皮疹且具有难以诊断的特征。其临床表现可与其他病症相似，使准确诊断变得复杂。本病例展示了一名74岁男性的AITL，该患者最初表现为贫血，类似于由B19微小病毒引起的纯红细胞贫血。患者出现直接抗人球蛋白试验阳性贫血和反复发作的荨麻疹样皮疹，这些最初具有误导性。该病例强调了对于出现直接抗人球蛋白试验阳性贫血和反复发作的荨麻疹样皮疹的患者考虑淋巴瘤的迫切需求。它强调了重新审视并全面评估病史以实现准确诊断的重要性，即使初始表现提示其他诊断。早期识别和适当管理AITL对于改善患者预后至关重要。
