Department of Neurology, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Department of Neurology, The Affiliated Chengdu 363 Hospital of Southwest Medical University, Chengdu, China.
Am J Alzheimers Dis Other Demen. 2024 Jan-Dec;39:15333175241271910. doi: 10.1177/15333175241271910.
Neuropsychological test batteries, which accurately and comprehensively assess cognitive functions, are a crucial approach in the early detection of and interventions for cognitive impairments. However, these tests have yet to gain wide clinical application in China owing to their complexity and time-consuming nature. This study aimed to develop the Computerized Neurocognitive Battery for Chinese-Speaking participants (CNBC), an autorun and autoscoring cognitive assessment tool to provide efficient and accurate cognitive evaluations for Chinese-Speaking individuals.
The CNBC was developed through collaboration between clinical neurologists and software engineers. Qualified volunteers were recruited to complete CNBC and traditional neurocognitive batteries. The reliability and validity of the CNBC were evaluated by analyzing the correlations between the measurements obtained from the computerized and the paper-based assessment and those between software-based scoring and manual scoring.
The CNBC included 4 subtests and an autorun version. Eighty-six volunteers aged 51-82 years with 7-22 years of education were included. Significant correlations (0.256-0.666) were observed between paired measures associated with attention, executive function, and episodic memory from the CNBC and the traditional paper-based neurocognitive batteries. This suggests a strong construct validity of the CNBC in assessing these cognitive domains. Furthermore, the correlation coefficients between manual scoring and system scoring ranged from 0.904-1.0, indicating excellent inter-rater reliability for the CNBC.
A novel CNBC equipped with automated testing and scoring features was developed in this study. The preliminary results confirm its strong reliability and validity, indicating its promising potential for clinical utilization.
神经心理学测试组合可准确、全面地评估认知功能，是早期发现和干预认知障碍的重要方法。然而，由于其复杂性和耗时性，这些测试尚未在中国得到广泛的临床应用。本研究旨在开发一种针对汉语使用者的计算机化神经认知测试组合（CNBC），这是一种自动运行和自动评分的认知评估工具，可为汉语使用者提供高效、准确的认知评估。
CNBC 由临床神经科医生和软件工程师合作开发。合格的志愿者被招募来完成 CNBC 和传统的神经认知测试组合。通过分析计算机化和纸质评估之间的测量值之间以及基于软件的评分和手动评分之间的相关性，评估了 CNBC 的信度和效度。
CNBC 包括 4 个子测试和一个自动运行版本。纳入了 86 名年龄在 51-82 岁之间、受教育年限为 7-22 年的志愿者。从 CNBC 和传统的纸质神经认知测试组合中获得的注意力、执行功能和情景记忆相关的配对测量值之间存在显著相关性（0.256-0.666）。这表明 CNBC 在评估这些认知领域具有很强的结构效度。此外，手动评分和系统评分之间的相关系数范围为 0.904-1.0，表明 CNBC 具有极好的评分者间信度。
本研究开发了一种具有自动测试和评分功能的新型 CNBC。初步结果证实了其强大的信度和效度，表明其在临床应用方面具有广阔的应用前景。
