3rd Department of Internal Medicine and Cardiology, Medical University of Warsaw, Warsaw, Poland.
Doctoral School, Medical University of Warsaw, Warsaw, Poland.
Sci Rep. 2024 Oct 4;14(1):23133. doi: 10.1038/s41598-024-73730-z.
Peak oxygen pulse (OP) is an important index of cardiorespiratory fitness (CRF). The FRIEND database is a global source of reference values for CRF. However, no reference equation is tailored for endurance athletes (EA) to predict OP. Here, we adjusted the well-established FRIEND equation for OP to the characteristics of the EA population. 32 (34.0%) female EA and 62 (66.0%) male well-trained EA underwent maximal cardiopulmonary exercise test on a treadmill. V̇O was 4.5 ± 0.5 L min in males and 3.1 ± 0.4 L min in females. OP was 23.6 ± 2.8 mL beat and 16.4 ± 2.0 mL beat for males and females, respectively. Firstly, we externally validated the original FRIEND equation. Secondly, using multiple linear regression, we adjusted the FRIEND equation for OP to the population of EA. The original FRIEND equation underestimated OP for 2.9 ± 2.9 mL beat (P < .001) in males and 2.2 ± 2.1 mL beat (P < .001) in females. The updated equation was 1.36 + 1.07 (23.2 · 0.09 · age - 6.6 [if female]). The new equation explained 62% of the variance and significantly predicted OP (R = 0.62, β = 0.78, P < .001). The error of the EA-adjusted model was 0.1 ± 2.9 mL beat (P = .82) and 0.2 ± 2.1 mL beat (P = .65) for males and females respectively. Recalibration of the original FRIEND equation significantly enhances its accuracy among EA. The error of the EA-adjusted model was negligible. A new recalibrated equation should be used to predict OP in the population of EA.
峰值摄氧量（OP）是心肺适能（CRF）的一个重要指标。FRIEND 数据库是全球 CRF 参考值的来源。然而，目前还没有针对耐力运动员（EA）的预测 OP 的参考方程。在这里，我们调整了成熟的 FRIEND 方程，使其适用于 EA 人群的特点。32 名（34.0%）女性 EA 和 62 名（66.0%）男性训练有素的 EA 在跑步机上进行了最大心肺运动测试。男性 V̇O 为 4.5±0.5 L min，女性为 3.1±0.4 L min。男性和女性的 OP 分别为 23.6±2.8 mL beat 和 16.4±2.0 mL beat。首先，我们对外验证了原始的 FRIEND 方程。其次，我们使用多元线性回归，将 FRIEND 方程调整为 EA 人群的 OP。原始的 FRIEND 方程低估了男性的 OP 2.9±2.9 mL beat（P<.001）和女性的 OP 2.2±2.1 mL beat（P<.001）。更新后的方程为 1.36+1.07（23.2·0.09·年龄-6.6[如果女性]）。新方程解释了 62%的方差，并且显著预测了 OP（R=0.62，β=0.78，P<.001）。EA 调整模型的误差为男性 0.1±2.9 mL beat（P=.82）和女性 0.2±2.1 mL beat（P=.65）。对原始 FRIEND 方程的重新校准显著提高了其在 EA 中的准确性。EA 调整模型的误差可以忽略不计。应该使用新的重新校准方程来预测 EA 人群的 OP。
