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免疫系统中的生长激素释放激素。

Growth hormone - releasing hormone in the immune system.

作者信息

Siejka Agnieszka, Lawnicka Hanna, Fakir Saikat, Barabutis Nektarios

机构信息

Department of Clinical Endocrinology, Medical University of Lodz, Lodz, Poland.

Department of Immunoendocrinology, Medical University of Lodz, Lodz, Poland.

出版信息

Rev Endocr Metab Disord. 2024 Oct 7. doi: 10.1007/s11154-024-09913-w.

DOI:10.1007/s11154-024-09913-w
PMID:39370499
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11973240/
Abstract

GHRH is a neuropeptide associated with a diverse variety of activities in human physiology and immune responses. The present study reviews the latest information on the involvement of GHRH in the immune system and inflammation, suggesting that GHRH antagonists may deliver a new therapeutic possibility in disorders related to immune system dysfunction and inflammation.

摘要

生长激素释放激素（GHRH）是一种神经肽，与人类生理学和免疫反应中的多种活动相关。本研究综述了关于GHRH参与免疫系统和炎症的最新信息，表明GHRH拮抗剂可能为与免疫系统功能障碍和炎症相关的疾病提供一种新的治疗可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24cb/12137409/6fc7cefd2454/11154_2024_9913_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24cb/12137409/6fc7cefd2454/11154_2024_9913_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24cb/12137409/6fc7cefd2454/11154_2024_9913_Fig1_HTML.jpg

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Mention to Prof. Andrew V. Schally.向安德鲁·V·沙利教授提及。

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NEK-mediated barrier regulation.Nek 介导的屏障调节。
Pulm Pharmacol Ther. 2024 Sep;86:102313. doi: 10.1016/j.pupt.2024.102313. Epub 2024 Jun 21.
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Protective Activities of Growth Hormone-Releasing Hormone Antagonists against Toxin-Induced Endothelial Injury.生长激素释放激素拮抗剂对毒素诱导的内皮损伤的保护作用。
Rev Endocr Metab Disord. 2025 Mar 17. doi: 10.1007/s11154-025-09956-7.
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Tissue Cell. 2025 Jun;94:102811. doi: 10.1016/j.tice.2025.102811. Epub 2025 Feb 28.
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Rev Endocr Metab Disord. 2025 Jan 30. doi: 10.1007/s11154-024-09939-0.
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