Key Laboratory of Macromolecular Science of Shaanxi Province, Shaanxi Key Laboratory for Advanced Energy Devices, Shaanxi Engineering Laboratory for Advanced Energy Technology, School of Chemistry & Chemical Engineering, Shaanxi Normal University, Xi'an, Shaanxi Province 710062, PR China.
College of Chemistry and Chemical Engineering, Shaanxi Key Laboratory of Chemical Additives for Industry, Shaanxi University of Science and Technology, Xi'an, Shaanxi Province 710021, PR China.
Inorg Chem. 2024 Oct 21;63(42):19652-19664. doi: 10.1021/acs.inorgchem.4c02773. Epub 2024 Oct 6.
Quantitative detection of tetracycline (TC) and nitrofurantoin (NFT) in food and water is of importance for food safety and environmental protection. Herein, Zn was introduced into a europium metal-organic framework Eu-bpdc (Hbpdc = 2,2'-bipyridyl-5,5'-dicarboxylic acid) to prepare a composite of Zn@Eu-bpdc, which was developed as a fluorescence sensor for TC and NFT. The fluorescence mechanism concerns with bpdc ligand-to-Eu(III) charge transfer, and the detection mechanism is the inner filter effect. Zn@Eu-bpdc is a ratiometric fluorescence sensor for TC with the linear fitting equation of / = 1.94 × 10 M, whose limit of detection (LOD) is 0.148 μmol·L (μM); it is also a fluorescence "turn-off" sensor for NFT with the fitting equation of (-)/ = 3.62 × 10 M and LOD = 0.0792 μM. Zn@Eu-bpdc can detect TC or NFT in lake water, honey, and milk with high accuracy. The emission color changes of paper-based Zn@Eu-bpdc depending on or reveal the visualization detections of TC and NFT. With the red and green values as input signals, smartphone-assisted on-site detection is utilized to recognize the antibiotic residuals of TC and NFT by a self-programmed APP. Zn@Eu-bpdc is promising in a smartphone-assisted intelligent platform for on-site detection of TC and NFT.
定量检测食品和水中的四环素（TC）和呋喃妥因（NFT）对于食品安全和环境保护至关重要。在此，我们将锌引入到铕金属有机框架 Eu-bpdc（Hbpdc = 2,2'-联吡啶-5,5'-二羧酸）中，制备了 Zn@Eu-bpdc 复合材料，将其开发为 TC 和 NFT 的荧光传感器。荧光机制涉及 bpdc 配体到 Eu(III)的电荷转移，检测机制是内滤效应。Zn@Eu-bpdc 是一种用于 TC 的比率荧光传感器，其线性拟合方程为 I = 1.94 × 10 M，检测限（LOD）为 0.148 μmol·L（μM）；它也是 NFT 的荧光“关闭”传感器，拟合方程为 (-)/ = 3.62 × 10 M，LOD = 0.0792 μM。Zn@Eu-bpdc 可以高精度地检测湖水、蜂蜜和牛奶中的 TC 或 NFT。基于纸张的 Zn@Eu-bpdc 的发射颜色变化取决于 或 ，可以可视化检测 TC 和 NFT。将红色和绿色值作为输入信号，利用智能手机辅助现场检测，通过自编的 APP 识别 TC 和 NFT 的抗生素残留。Zn@Eu-bpdc 有望成为智能手机辅助的现场检测 TC 和 NFT 的智能平台。
