Department of Chemical Sciences, University of Johannesburg, Doornfontein, 2028, South Africa.
Centre for Nanomaterials Science Research, University of Johannesburg, South Africa.
Anal Methods. 2024 Nov 14;16(44):7518-7526. doi: 10.1039/d4ay01257g.
Towards the nicotine addiction challenge in the smoking of hookah pipe products, we hereby present the development of an electrochemical sensor for nicotine detection. A nitrogen-doped carbon nanosheet (N-CNS)/poly(amidoamine) dendrimer (PAMAM) nanocomposite-modified electrode was prepared as a sensor for the detection of nicotine in analytical and real samples. The N-CNSs were prepared by a hydrothermal method and dropcast on a glassy carbon electrode followed by electro-deposition of the PAMAM dendrimer to form the sensor (GCE/N-CNSs/PAMAM). The N-CNSs were characterized with electron microscopy, Raman spectroscopy and FTIR. The sensor was characterized with voltammetry and electrochemical impedance spectroscopy. The N-CNS/PAMAM enhanced the electrochemical performance of the electrode towards the oxidation of nicotine. The sensor achieved a detection limit of 0.05 μM in a linear concentration range of 1.93-61.64 μM nicotine standard samples. The sensor showed good reproducibility, repeatability, and selectivity. The sensor was successful in selectively detecting nicotine in two local brands of hookah pipe tobacco with a 113-121 percent recovery. Nicotine, up to a concentration of 0.35-0.39 mg g, was found in the sampled hookah pipe tobacco products suggesting possible harm to human health.
针对水烟筒产品吸烟中的尼古丁成瘾挑战，我们在此提出一种用于尼古丁检测的电化学传感器的发展。一种氮掺杂碳纳米片（N-CNS）/聚（酰胺-胺）树枝状大分子（PAMAM）纳米复合材料修饰电极被制备为用于分析和实际样品中尼古丁检测的传感器。N-CNSs 通过水热法制备，并滴涂在玻碳电极上，然后电沉积 PAMAM 树枝状大分子以形成传感器（GCE/N-CNSs/PAMAM）。N-CNSs 用电子显微镜、拉曼光谱和 FTIR 进行了表征。传感器用伏安法和电化学阻抗谱进行了表征。N-CNS/PAMAM 增强了电极对尼古丁氧化的电化学性能。该传感器在 1.93-61.64 μM 尼古丁标准样品的线性浓度范围内实现了 0.05 μM 的检测限。该传感器表现出良好的重现性、重复性和选择性。该传感器成功地选择性地检测了两种当地品牌水烟筒烟草中的尼古丁，回收率为 113-121%。在所采样的水烟筒烟草产品中发现尼古丁的浓度高达 0.35-0.39mg/g，这表明可能对人体健康造成危害。
