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膝骨关节炎——当前的诊断与治疗选择——一篇叙述性综述

Knee Osteoarthritis-Current Diagnosis and Treatment Options-A Narrative Review.

作者信息

Cioroianu George-Ovidiu, Florescu Alesandra, Florescu Lucian-Mihai, Rogoveanu Otilia-Constantina

机构信息

Student, Doctoral School, University of Medicine and Pharmacy of Craiova, Romania.

Department of Physical Medicine and Rehabilitation, University of Medicine and Pharmacy of Craiova, Romania.

出版信息

Curr Health Sci J. 2024 Apr-Jun;50(2):163-169. doi: 10.12865/CHSJ.50.02.01. Epub 2024 Jun 30.

DOI:10.12865/CHSJ.50.02.01
PMID:39371059
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11447502/
Abstract

Knee osteoarthritis (KOA) represents a progressive and painful disease that in time can lead to loss of function and disability. Early diagnosis and correct treatment are essential in preventing the advancement of the condition to a stage where it can affect the quality of life. The development of new imagistic methods and devices can help detect changes in the structure of the join before the onset of symptoms. At the moment there are no disease- modifying drugs approved, so the current treatment is symptomatic, focusing on pain reduction, improving function and trying to prevent progression towards disability.

摘要

膝关节骨关节炎（KOA）是一种渐进性疼痛疾病，随着时间推移可能导致功能丧失和残疾。早期诊断和正确治疗对于防止病情发展到影响生活质量的阶段至关重要。新成像方法和设备的发展有助于在症状出现前检测关节结构的变化。目前尚无获批的改善病情药物，因此当前治疗以对症治疗为主，重点是减轻疼痛、改善功能并试图防止病情发展至残疾。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e286/11447502/aabdb587bcba/CHSJ-50-02-163-fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e286/11447502/9a5e2e54a486/CHSJ-50-02-163-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e286/11447502/dbe9a56244bb/CHSJ-50-02-163-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e286/11447502/3ab44d7b5920/CHSJ-50-02-163-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e286/11447502/35f415929a0f/CHSJ-50-02-163-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e286/11447502/723a206d8772/CHSJ-50-02-163-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e286/11447502/aabdb587bcba/CHSJ-50-02-163-fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e286/11447502/9a5e2e54a486/CHSJ-50-02-163-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e286/11447502/dbe9a56244bb/CHSJ-50-02-163-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e286/11447502/3ab44d7b5920/CHSJ-50-02-163-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e286/11447502/35f415929a0f/CHSJ-50-02-163-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e286/11447502/723a206d8772/CHSJ-50-02-163-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e286/11447502/aabdb587bcba/CHSJ-50-02-163-fig6.jpg

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Clinical Evaluation of the Knee Arthritis Patient.膝关节关节炎患者的临床评估。
Tech Vasc Interv Radiol. 2023 Mar;26(1):100876. doi: 10.1016/j.tvir.2022.100876. Epub 2022 Dec 22.
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How does hip osteoarthritis differ from knee osteoarthritis?髋关节骨关节炎与膝关节骨关节炎有何不同？
关节内注射透明质酸和富血小板血浆作为膝骨关节炎的单一疗法或联合疗法？
Regen Med. 2024 Dec;19(12):637-644. doi: 10.1080/17460751.2024.2439221. Epub 2024 Dec 11.
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Recent Updates of Diagnosis, Pathophysiology, and Treatment on Osteoarthritis of the Knee.膝关节骨关节炎的诊断、病理生理学和治疗的最新进展。
Int J Mol Sci. 2021 Mar 5;22(5):2619. doi: 10.3390/ijms22052619.
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Osteoarthritis of the Knee.膝关节骨关节炎
N Engl J Med. 2021 Jan 7;384(1):51-59. doi: 10.1056/NEJMcp1903768.
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