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乳腺腺肌上皮瘤:一例报告

Adenomyoepithelioma of the Breast: A Case Report.

作者信息

Rellias Ioannis, Spanou Kallirroi

机构信息

Breast Surgery, Athens Euroclinic, Athens, GRC.

Breast Unit, Department of Obstetrics and Gynecology, National and Kapodistrian University of Athens, Alexandra General Hospital, Athens, GRC.

出版信息

Cureus. 2024 Sep 6;16(9):e68812. doi: 10.7759/cureus.68812. eCollection 2024 Sep.

DOI:10.7759/cureus.68812
PMID:39371834
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11456320/
Abstract

Adenomyoepithelioma (AME) is an uncommon breast tumor distinguished by the presence of both epithelial and myoepithelial cell proliferation. It often presents clinically as a well-circumscribed, non-painful mass, although it can also be asymptomatic and discovered incidentally during imaging. This case report describes a 32-year-old woman with a tumor that progressively increased in size. It was initially assessed as a fibroadenoma based on ultrasonography and MRI, as the patient declined to undergo a core needle biopsy. The tumor poses significant diagnostic challenges due to its diverse imaging characteristics, necessitating a core needle biopsy for initial identification. There is also considerable variability within different regions of the same tumor, and surgical removal is typically recommended for most cases of AME. Most AMEs are benign, but they have the potential for local recurrence after surgical excision and, in rare cases, can become malignant. Accurate diagnosis and appropriate management can be achieved through clinical suspicion during examination, combined with the use of radiological techniques and histopathological analysis.

摘要

腺肌上皮瘤(AME)是一种罕见的乳腺肿瘤,其特征是上皮细胞和肌上皮细胞均有增殖。临床上它常表现为边界清晰、无痛性肿块,不过也可能无症状,在影像学检查时偶然发现。本病例报告描述了一名32岁女性,其肿瘤大小逐渐增大。最初根据超声和磁共振成像评估为纤维腺瘤,因为患者拒绝接受粗针活检。由于其多样的影像学特征,该肿瘤带来了重大的诊断挑战,需要进行粗针活检以进行初步识别。同一肿瘤的不同区域也存在相当大的变异性,大多数AME病例通常建议手术切除。大多数AME是良性的,但手术切除后有局部复发的可能,极少数情况下会恶变。通过检查时的临床怀疑,结合放射学技术和组织病理学分析,可以实现准确诊断和恰当处理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92cb/11456320/d1ec95725fba/cureus-0016-00000068812-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92cb/11456320/35e19001f296/cureus-0016-00000068812-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92cb/11456320/3bf1162b6874/cureus-0016-00000068812-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92cb/11456320/8fe517affe8f/cureus-0016-00000068812-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92cb/11456320/0e4038d0e474/cureus-0016-00000068812-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92cb/11456320/80e7969c0122/cureus-0016-00000068812-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92cb/11456320/66f86c2c0573/cureus-0016-00000068812-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92cb/11456320/e56b15b59f4a/cureus-0016-00000068812-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92cb/11456320/d1ec95725fba/cureus-0016-00000068812-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92cb/11456320/35e19001f296/cureus-0016-00000068812-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92cb/11456320/3bf1162b6874/cureus-0016-00000068812-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92cb/11456320/8fe517affe8f/cureus-0016-00000068812-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92cb/11456320/0e4038d0e474/cureus-0016-00000068812-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92cb/11456320/80e7969c0122/cureus-0016-00000068812-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92cb/11456320/66f86c2c0573/cureus-0016-00000068812-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92cb/11456320/e56b15b59f4a/cureus-0016-00000068812-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92cb/11456320/d1ec95725fba/cureus-0016-00000068812-i08.jpg

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本文引用的文献

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Adenomyoepithelioma of the breast with malignant transformation and repeated local recurrence: A case report.乳腺腺肌上皮瘤伴恶性转化及反复局部复发:1例报告
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Benign adenomyoepitelioma of the breast: Presentation of two rare cases and review of literature.
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