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股动脉血管成形术后不久出现蜂窝织炎特征的Sweet综合征

Sweet Syndrome Presenting with Features of Cellulitis Shortly after Femoral Angioplasty.

作者信息

Wang Qi, Sinclair John, Amaravadi Ayyappa, Arioride Onovughe

机构信息

Internal Medicine, Unity Hospital/Rochester Regional Health, Rochester, USA.

出版信息

Eur J Case Rep Intern Med. 2024 Sep 24;11(10):004670. doi: 10.12890/2024_004670. eCollection 2024.

DOI:10.12890/2024_004670
PMID:39372146
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11451857/
Abstract

UNLABELLED

Neutrophilic dermatosis, or Sweet syndrome, is a cutaneous disorder caused by neutrophilic infiltration in the upper dermis. It has been associated with medications, infections and malignancies but to date it has not been associated with femoral arterial angioplasty or stenting. We present the case of a 75-year-old female who, after angioplasty and stent placement of the right superficial femoral artery, developed right heel pain with ulceration that did not respond to broad antibiotics. She underwent incision and drainage twice without improvement; both times produced negative cultures. She then underwent a punch biopsy by dermatology, which was consistent with acute spongiotic and other neutrophilic dermatoses. She was started on prednisone with immediate improvement of her symptoms. She was discharged to a rehabilitation centre with a prednisone taper and antibiotics. This report highlights the importance of maintaining Sweet syndrome on the differential for cellulitis as it is a rare mimicry of other infectious and non-infectious aetiologies, which are common in the perioperative space. Early treatment is crucial to improve symptoms, outcomes, healthcare cost and potentially the length of stay.

LEARNING POINTS

Sweet syndrome, a rare skin condition related to neutrophil infiltration, may be triggered by angioplasty.Sweet syndrome is easily misdiagnosed as infectious conditions such as cellulitis.

摘要

未标注

嗜中性皮肤病,即斯威特综合征,是一种由真皮上层嗜中性粒细胞浸润引起的皮肤疾病。它与药物、感染和恶性肿瘤有关,但迄今为止尚未与股动脉血管成形术或支架置入术相关联。我们报告一例75岁女性病例,该患者在右股浅动脉进行血管成形术和支架置入术后,出现右足跟疼痛伴溃疡,使用广谱抗生素治疗无效。她接受了两次切开引流均无改善,两次培养结果均为阴性。随后皮肤科进行了打孔活检,结果与急性海绵状及其他嗜中性皮肤病相符。她开始使用泼尼松治疗,症状立即改善。她出院后前往康复中心,逐渐减少泼尼松用量并继续使用抗生素。本报告强调了在鉴别蜂窝织炎时考虑斯威特综合征的重要性,因为它是一种罕见的模仿其他感染性和非感染性病因的疾病,而这些病因在围手术期很常见。早期治疗对于改善症状、预后、医疗成本以及可能的住院时间至关重要。

学习要点

斯威特综合征是一种与嗜中性粒细胞浸润相关的罕见皮肤病,可能由血管成形术引发。斯威特综合征很容易被误诊为蜂窝织炎等感染性疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4a6/11451857/ef75b007111f/4670_Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4a6/11451857/23ab0298c2c0/4670_Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4a6/11451857/593f51827aa4/4670_Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4a6/11451857/ef75b007111f/4670_Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4a6/11451857/23ab0298c2c0/4670_Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4a6/11451857/593f51827aa4/4670_Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4a6/11451857/ef75b007111f/4670_Fig3.jpg

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Sweet Syndrome: A Review of Published Cases.Sweet 综合征:已发表病例回顾。
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