Laws J Lukas, Maya Tania Ruiz, Gupta Deepak K
Vanderbilt Translational and Clinical Cardiovascular Research Center, Division of Cardiovascular Medicine, Vanderbilt University Medical Center, 2525 West End Ave, Suite 300, Nashville, TN, 37203, USA.
Curr Cardiol Rep. 2024 Dec;26(12):1461-1469. doi: 10.1007/s11886-024-02142-2. Epub 2024 Oct 7.
Diastolic dysfunction is an important, though often underappreciated, cause for exertional dyspnea. Echocardiography enables noninvasive evaluation of diastolic function and filling pressure, but images acquired at rest may be insensitive for detection of exertional abnormalities. This review focuses on stress echocardiography to assess diastolic function, including traditional and novel techniques, with emphasis on specific patient sub-groups in whom this testing may be valuable.
Emerging data informs patient selection for diastolic stress testing. Further, increasing literature provides considerations for performance and interpretation of diastolic metrics relevant to patients with heart failure with preserved ejection fraction, hypertrophic cardiomyopathy, athletes, and those with microvascular coronary dysfunction. Methods, such as speckle-tracking and multi-modality imaging, provide additional and complementary information for non-invasive diastolic assessment. This review serves as a guide to optimally utilize existing and novel techniques of stress echocardiography for diastolic assessment across a broad range of patients.
舒张功能障碍是劳力性呼吸困难的一个重要原因,尽管常常未得到充分认识。超声心动图能够对舒张功能和充盈压进行无创评估,但静息状态下获取的图像对于检测劳力性异常可能不敏感。本综述重点关注用于评估舒张功能的负荷超声心动图,包括传统技术和新技术,特别强调了该检测可能具有价值的特定患者亚组。
新出现的数据为舒张期负荷试验的患者选择提供了依据。此外,越来越多的文献为与射血分数保留的心力衰竭患者、肥厚型心肌病患者、运动员以及微血管性冠状动脉功能障碍患者相关的舒张期指标的测量和解读提供了考量。散斑追踪和多模态成像等方法为无创舒张期评估提供了额外的补充信息。本综述旨在指导如何在广泛的患者群体中最佳地利用现有的和新的负荷超声心动图技术进行舒张期评估。