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老年患者常规单切口腹腔镜胆总管探查术同期胆囊切除术:6 年回顾性对比研究。

Routine single-incision laparoscopic common bile duct exploration with concomitant cholecystectomy for elderly patients: a 6-year retrospective comparative study.

机构信息

Division of General and Digestive Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.

School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.

出版信息

Surg Endosc. 2024 Nov;38(11):6963-6972. doi: 10.1007/s00464-024-11277-w. Epub 2024 Oct 7.

Abstract

BACKGROUND

While single-incision laparoscopic cholecystectomy (SILC) has gained more popularity in recent years, its application to elderly patients needs further evaluation. Few SILC studies regarded this rapidly growing vulnerable population, and single-incision laparoscopic common bile duct exploration (SILCBDE) was never mentioned. We conducted an observational study of 146 routine SILCBDE to address this issue.

METHODS

One hundred forty-six consecutive patients underwent SILCBDE with concomitant cholecystectomies during a period of 6 years (July 2012-June 2016 and July 2018-July 2020). Forty patients with an age of 65 years or older were the study target. Characteristics and operative outcomes were compared with the remaining 106 younger patients by retrospective chart review. The primary outcomes include complications and mortality, while the secondary outcomes contain intraoperative blood loss, operative time, procedural conversions, postoperative length of hospital stay, and bile duct stone recurrence.

RESULTS

There was no mortality. The bile duct stone clearance rate was 98.6%. The elderly group had higher American Society of Anesthesiologists (ASA) scores, higher comorbidity rate, higher acute cholangitis rate, lower completion intraoperative cholangiography (IOC) rate, longer operative time, more blood loss, longer postoperative hospital stay (p < .001), longer total hospital stay (p < .001), higher procedural conversion rate (p < .05), higher complication rate (p < .001), and the exclusive open conversion (2.5%). The difference in complications derived from Clavien-Dindo grade I.

CONCLUSION

Routine SILCBDE with concomitant cholecystectomy by experienced surgeons is safe and efficacious for elderly patients as for younger patients. Randomized controlled trials are anticipated.

摘要

背景

虽然单切口腹腔镜胆囊切除术(SILC)近年来越来越受欢迎,但在老年患者中的应用仍需进一步评估。很少有 SILC 研究关注这一快速增长的脆弱人群,也从未提到过单切口腹腔镜胆总管探查术(SILCBDE)。我们对 146 例行 SILCBDE 进行了观察性研究,以解决这个问题。

方法

在 6 年的时间里(2012 年 7 月至 2016 年 6 月和 2018 年 7 月至 2020 年 7 月),146 例连续患者接受了 SILCBDE 联合胆囊切除术。40 例年龄在 65 岁或以上的患者为研究对象。通过回顾性病历回顾,比较了 106 例年轻患者的特征和手术结果。主要结果包括并发症和死亡率,次要结果包括术中出血量、手术时间、手术转换、术后住院时间和胆管结石复发。

结果

无死亡病例。胆管结石清除率为 98.6%。老年组的美国麻醉医师协会(ASA)评分较高,合并症发生率较高,急性胆管炎发生率较高,术中完成胆管造影(IOC)率较低,手术时间较长,出血量较多,术后住院时间较长(p<.001),总住院时间较长(p<.001),手术转换率较高(p<.05),并发症发生率较高(p<.001),且完全转为开放性手术(2.5%)。并发症差异来源于 Clavien-Dindo 分级 I。

结论

经验丰富的外科医生行常规 SILCBDE 联合胆囊切除术,对老年患者和年轻患者同样安全有效。预计将进行随机对照试验。

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