U. S. Geological Survey, Eastern Ecological Science Center, Laurel, MD, USA.
Rubenstein School of Environment and Natural Resources, University of Vermont, Burlington, VT, USA.
Nat Commun. 2024 Oct 7;15(1):8677. doi: 10.1038/s41467-024-52737-0.
One Health aims to achieve optimal health outcomes for people, animals, plants, and shared environments. We describe a multisector effort to understand and mitigate SARS-CoV-2 transmission risk to humans via the spread among and between captive and wild white-tailed deer. We first framed a One Health problem with three governance sectors that manage captive deer, wild deer populations, and public health. The problem framing included identifying fundamental objectives, causal chains for transmission, and management actions. We then developed a dynamic model that linked deer herds and simulated SARS-CoV-2. Next, we evaluated management alternatives for their ability to reduce SARS-CoV-2 spread in white-tailed deer. We found that single-sector alternatives reduced transmission, but that the best-performing alternative required collaborative actions among wildlife management, agricultural management, and public health agencies. Here, we show quantitative support that One Health actions outperform single-sector responses, but may depend on coordination to track changes in this evolving system.
One Health 旨在实现人类、动物、植物和共享环境的最佳健康结果。我们描述了一项多部门的努力，以了解和减轻通过圈养和野生白尾鹿之间和之间的传播对人类的 SARS-CoV-2 传播风险。我们首先确定了三个管理部门的 One Health 问题，这些部门管理着圈养鹿、野生鹿种群和公共卫生。问题框架包括确定基本目标、传播的因果链和管理措施。然后，我们开发了一个动态模型，将鹿群和 SARS-CoV-2 联系起来。接下来，我们评估了管理替代方案减少白尾鹿中 SARS-CoV-2 传播的能力。我们发现，单一部门的替代方案减少了传播，但表现最好的替代方案需要野生动物管理、农业管理和公共卫生机构之间的协作行动。在这里，我们展示了定量支持，表明 One Health 行动优于单一部门的反应，但可能取决于协调以跟踪这个不断发展的系统中的变化。
