野生白尾鹿感染严重急性呼吸综合征冠状病毒2（SARS-CoV-2）（） 。 （你提供的原文括号里内容缺失，翻译可能不太完整准确，你可补充完整后继续让我翻译 ）
SARS-CoV-2 exposure in wild white-tailed deer ().
作者信息
Chandler Jeffrey C, Bevins Sarah N, Ellis Jeremy W, Linder Timothy J, Tell Rachel M, Jenkins-Moore Melinda, Root J Jeffrey, Lenoch Julianna B, Robbe-Austerman Suelee, DeLiberto Thomas J, Gidlewski Thomas, Kim Torchetti Mia, Shriner Susan A
机构信息
National Wildlife Research Center, Wildlife Services, Animal and Plant Health Inspection Service, US Department of Agriculture, Fort Collins, CO 80521.
National Wildlife Disease Program, Wildlife Services, Animal and Plant Health Inspection Service, US Department of Agriculture, Fort Collins, CO 80521.
出版信息
Proc Natl Acad Sci U S A. 2021 Nov 23;118(47). doi: 10.1073/pnas.2114828118.
Widespread human SARS-CoV-2 infections combined with human-wildlife interactions create the potential for reverse zoonosis from humans to wildlife. We targeted white-tailed deer () for serosurveillance based on evidence these deer have angiotensin-converting enzyme 2 receptors with high affinity for SARS-CoV-2, are permissive to infection, exhibit sustained viral shedding, can transmit to conspecifics, exhibit social behavior, and can be abundant near urban centers. We evaluated 624 prepandemic and postpandemic serum samples from wild deer from four US states for SARS-CoV-2 exposure. Antibodies were detected in 152 samples (40%) from 2021 using a surrogate virus neutralization test. A subset of samples tested with a SARS-CoV-2 virus neutralization test showed high concordance between tests. These data suggest white-tailed deer in the populations assessed have been exposed to SARS-CoV-2.
广泛的人类新冠病毒感染与人类和野生动物的相互作用，使得病毒从人类反向传播到野生动物（即反向人畜共患病）成为可能。基于以下证据，我们将白尾鹿作为血清学监测的目标：这些鹿具有与新冠病毒高亲和力的血管紧张素转换酶2受体，容易感染，病毒持续脱落，可传播给同种个体，表现出社交行为，且在城市中心附近数量众多。我们评估了来自美国四个州的野生鹿在疫情前和疫情后的624份血清样本，以检测其是否接触过新冠病毒。使用替代病毒中和试验在2021年采集的152份样本（40%）中检测到了抗体。用新冠病毒中和试验检测的一部分样本在两种检测之间显示出高度一致性。这些数据表明，在所评估的鹿群中，白尾鹿已接触过新冠病毒。
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