Karambolova K K, Snow G R, Anderson C
Calcif Tissue Int. 1985 Dec;37(6):665-8. doi: 10.1007/BF02554927.
Resorptive and formative characteristics of the periosteal and corticoendosteal envelopes of the ribs of intact and spayed Beagle dams were studied. Six 4-year-old Beagle dams were spayed at source and kept under observation for 12 months. Four intact age- and weight-matched Beagle dams were used as controls. Before euthanizing, all dams received tetracycline labeling of their bones. Histomorphometric analyses of resorptive and formative parameters of the periosteal and corticoendosteal envelopes were carried out blind. The results indicated that following oophorectomy, there is an increase in resorptive surfaces on the periosteum and corticoendosteum, and a decline of formative activity on these same envelopes. These changes were manifested to a greater extent on the corticoendosteum. The lack of ovarian hormones contributes to an increase in the mineralization lag-time on the periosteum. Although in both control and spayed dams a similar pattern of surface activity was observed on both envelopes investigated, the differences in degree may be attributable to the ovarian hormone withdrawal.
对完整和绝育的比格犬母犬肋骨的骨膜和皮质骨内膜包膜的吸收和形成特征进行了研究。6只4岁的比格犬母犬在来源地进行了绝育，并观察12个月。4只年龄和体重匹配的完整比格犬母犬用作对照。在安乐死之前，所有母犬的骨骼都接受了四环素标记。对骨膜和皮质骨内膜包膜的吸收和形成参数进行了盲法组织形态计量学分析。结果表明，卵巢切除术后，骨膜和皮质骨内膜的吸收表面增加，这些相同包膜上的形成活性下降。这些变化在皮质骨内膜上表现得更为明显。卵巢激素的缺乏导致骨膜矿化延迟时间增加。尽管在对照和绝育母犬中，在所研究的两个包膜上都观察到了相似的表面活性模式，但程度上的差异可能归因于卵巢激素的撤除。
