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探索模型复杂性对喉癌检测的影响。

Exploring the Impact of Model Complexity on Laryngeal Cancer Detection.

作者信息

Rao Divya, Singh Rohit, Koteshwara Prakashini, Vijayananda J

机构信息

Department of Information and Communication Technology, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, 576104 India.

Department of Otorhinolaryngology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, 576104 India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2024 Oct;76(5):4036-4042. doi: 10.1007/s12070-024-04776-8. Epub 2024 Jun 6.

DOI:10.1007/s12070-024-04776-8
PMID:39376269
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11455748/
Abstract

: Laryngeal cancer accounts for a third of all head and neck malignancies, necessitating timely detection for effective treatment and enhanced patient outcomes. Machine learning shows promise in medical diagnostics, but the impact of model complexity on diagnostic efficacy in laryngeal cancer detection can be ambiguous. : In this study, we examine the relationship between model sophistication and diagnostic efficacy by evaluating three approaches: Logistic Regression, a small neural network with 4 layers of neurons and a more complex convolutional neural network with 50 layers and examine their efficacy on laryngeal cancer detection on computed tomography images. : Logistic regression achieved 82.5% accuracy. The 4-Layer NN reached 87.2% accuracy, while ResNet-50, a deep learning architecture, achieved the highest accuracy at 92.6%. Its deep learning capabilities excelled in discerning fine-grained CT image features. : Our study highlights the choices involved in selecting a laryngeal cancer detection model. Logistic regression is interpretable but may struggle with complex patterns. The 4-Layer NN balances complexity and accuracy. ResNet-50 excels in image classification but demands resources. This research advances understanding affect machine learning model complexity could have on learning features of laryngeal tumor features in contrast CT images for purposes of disease prediction.

摘要

喉癌占所有头颈恶性肿瘤的三分之一,因此需要及时检测以进行有效治疗并改善患者预后。机器学习在医学诊断中显示出前景,但模型复杂性对喉癌检测诊断效能的影响可能并不明确。在本研究中,我们通过评估三种方法来考察模型复杂度与诊断效能之间的关系:逻辑回归、具有4层神经元的小型神经网络以及具有50层的更复杂的卷积神经网络,并考察它们在计算机断层扫描图像上检测喉癌的效能。逻辑回归的准确率达到82.5%。4层神经网络的准确率达到87.2%,而深度学习架构ResNet - 50的准确率最高,为92.6%。其深度学习能力在辨别细粒度CT图像特征方面表现出色。我们的研究突出了选择喉癌检测模型时涉及的各种考量。逻辑回归具有可解释性,但可能难以处理复杂模式。4层神经网络在复杂性和准确性之间取得了平衡。ResNet - 50在图像分类方面表现出色,但需要资源。这项研究增进了我们对于机器学习模型复杂性在对比CT图像中学习喉肿瘤特征以进行疾病预测方面可能产生的影响的理解。

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本文引用的文献

1
Machine-learning-assisted spontaneous Raman spectroscopy classification and feature extraction for the diagnosis of human laryngeal cancer.基于机器学习的自发 Raman 光谱分类和特征提取在人喉癌诊断中的应用。
Comput Biol Med. 2022 Jul;146:105617. doi: 10.1016/j.compbiomed.2022.105617. Epub 2022 May 18.
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Automated segmentation of the larynx on computed tomography images: a review.计算机断层扫描图像上喉部的自动分割:综述
Biomed Eng Lett. 2022 Mar 18;12(2):175-183. doi: 10.1007/s13534-022-00221-3. eCollection 2022 May.
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Overview on Molecular Biomarkers for Laryngeal Cancer: Looking for New Answers to an Old Problem.喉癌分子生物标志物概述:探寻一个老问题的新答案
Cancers (Basel). 2022 Mar 28;14(7):1716. doi: 10.3390/cancers14071716.
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Machine Learning Improves Prediction Over Logistic Regression on Resected Colon Cancer Patients.机器学习在接受结肠切除术的癌症患者中比逻辑回归能更好地进行预测。
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Logistic Regression in Clinical Studies.临床研究中的逻辑回归
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Artificial Intelligence-based methods in head and neck cancer diagnosis: an overview.基于人工智能的头颈部癌症诊断方法:综述。
Br J Cancer. 2021 Jun;124(12):1934-1940. doi: 10.1038/s41416-021-01386-x. Epub 2021 Apr 19.
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Detection and classification of breast cancer using logistic regression feature selection and GMDH classifier.使用逻辑回归特征选择和 GMDH 分类器进行乳腺癌检测和分类。
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8
Use of artificial intelligence in diagnosis of head and neck precancerous and cancerous lesions: A systematic review.人工智能在头颈部癌前病变和癌症诊断中的应用:系统评价。
Oral Oncol. 2020 Nov;110:104885. doi: 10.1016/j.oraloncology.2020.104885. Epub 2020 Jul 13.
9
Updates on larynx cancer epidemiology.喉癌流行病学的最新进展。
Chin J Cancer Res. 2020 Feb;32(1):18-25. doi: 10.21147/j.issn.1000-9604.2020.01.03.
10
The Treatment of Laryngeal Cancer.喉癌的治疗
Oral Maxillofac Surg Clin North Am. 2019 Feb;31(1):1-11. doi: 10.1016/j.coms.2018.09.001.