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一例罕见的小儿颈部肿块:累及脊柱的颈部脂肪母细胞瘤。

An Unusual Paediatric Neck Mass: Cervical Lipoblastoma with Spinal Involvement.

作者信息

Quah Gabriel Xia Peng, Aziz Azliana, Mohamad Hazama, Sheikh Ab Hamid Suzina, Ang Song Yee

机构信息

Department of Otorhinolaryngology-Head & Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia Health Campus, Kota Bharu, 16150 Kelantan Malaysia.

Department of Neurosciences, School of Medical Sciences, Hospital Universiti Sains Malaysia, Kota Bharu, Kelantan Malaysia.

出版信息

Indian J Otolaryngol Head Neck Surg. 2024 Oct;76(5):4673-4676. doi: 10.1007/s12070-024-04766-w. Epub 2024 Jun 6.

Abstract

Lipoblastoma is a benign tumour derived from embryonic white fat and is more commonly seen in children. Spinal involvement is rare, with only 14 cases reported to date. We report a case of a 7-year-old boy who was presented with an asymptomatic right neck swelling for 5 years. Clinical examination revealed a soft multilobulated mass causing tracheal deviation with normal neurological examination. Ultrasound, Computed tomography and Magnetic resonance imaging showed a lipomatous lesion with extension to spinal foramina at C3-C5 causing displacement of the spinal cord. Near total excision of the tumour was done with a small remnant left behind at C3-C4 as it was tightly adhered to the vertebral artery. Histopathological samples were consistent with lipoblastoma. The patient developed ipsilateral ptosis and pupillary myosis which improved on the second-month postoperative review; no other neurological deficit was noted, and a follow-up cervical MRI showed no recurrence.

摘要

脂肪母细胞瘤是一种源自胚胎白色脂肪的良性肿瘤,多见于儿童。脊柱受累情况罕见,迄今为止仅报告过14例。我们报告一例7岁男孩,其右侧颈部无症状肿胀已有5年。临床检查发现一个柔软的多叶状肿块,导致气管移位,神经系统检查正常。超声、计算机断层扫描和磁共振成像显示一个脂肪瘤样病变,延伸至C3 - C5的椎间孔,导致脊髓移位。肿瘤几乎完全切除,在C3 - C4处留下一小部分残余,因为它与椎动脉紧密粘连。组织病理学样本与脂肪母细胞瘤一致。患者出现同侧上睑下垂和瞳孔缩小,术后第二个月复查时有所改善;未发现其他神经功能缺损,随访颈部磁共振成像未显示复发。

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An Unusual Paediatric Neck Mass: Cervical Lipoblastoma with Spinal Involvement.一例罕见的小儿颈部肿块:累及脊柱的颈部脂肪母细胞瘤。
Indian J Otolaryngol Head Neck Surg. 2024 Oct;76(5):4673-4676. doi: 10.1007/s12070-024-04766-w. Epub 2024 Jun 6.
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本文引用的文献

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Adipocytic tumors in Children: A contemporary review.儿童脂肪细胞肿瘤:当代综述。
Semin Diagn Pathol. 2019 Mar;36(2):95-104. doi: 10.1053/j.semdp.2019.02.004. Epub 2019 Feb 28.
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Rare Complications of Cervical Spine Surgery: Horner's Syndrome.颈椎手术的罕见并发症:霍纳综合征。
Global Spine J. 2017 Apr;7(1 Suppl):103S-108S. doi: 10.1177/2192568216688184. Epub 2017 Apr 1.
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Spinal dumbbell lipoblastoma: a case-based update.脊髓哑铃状脂肪母细胞瘤:基于病例的最新进展
Childs Nerv Syst. 2016 Nov;32(11):2069-2073. doi: 10.1007/s00381-016-3184-1. Epub 2016 Jul 21.
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Intrapelvic lipoblastoma with massive spinal canal invasion.盆腔内脂肪母细胞瘤伴椎管广泛侵犯。
Childs Nerv Syst. 2007 May;23(5):581-5. doi: 10.1007/s00381-006-0242-0. Epub 2006 Dec 2.

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