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伴有眼眶受累的鼻型结外NK/T细胞淋巴瘤:常见表现的罕见实体

Nasal Extranodal NK/T Cell Lymphoma with Orbital Involvement: A Rare Entity of Common Presentations.

作者信息

Sharfudin Muhammad Hazim, Abu Bakar Muhammad Nasri, Abdul Manan Aifaa, Mohamad Umbaik Norsyamira Aida, Md Shukri Norasnieda

机构信息

Department of Otorhinolaryngology, Hospital Sultan Ismail Petra, Kuala Krai, Kelantan 18000 Malaysia.

Department of Otorhinolaryngology-Head and Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan 16150 Malaysia.

出版信息

Indian J Otolaryngol Head Neck Surg. 2024 Oct;76(5):4740-4743. doi: 10.1007/s12070-024-04818-1. Epub 2024 Jun 20.

Abstract

Nasal Extranodal NK/T Cell Lymphoma is an aggressive tumour affecting the nasal and midline structures, causing surrounding tissue destruction as the result of its progression. The initial presentations are similar to symptoms of benign nasal polyps, such as nasal obstruction, hyposmia and nasal discharge. As the disease progresses, the involvement of the palate, paranasal sinuses, orbit and skin become alarming symptoms. We report a case of a young male with Nasal ENKTL who presented with symptoms similar to acute on chronic rhinosinusitis with orbital complications. The challenges of diagnosing and getting to the correct management pathway are discussed.

摘要

鼻结外NK/T细胞淋巴瘤是一种侵袭性肿瘤,累及鼻腔和中线结构,随着病情进展可导致周围组织破坏。其初始表现与鼻息肉等良性疾病的症状相似,如鼻塞、嗅觉减退和流涕。随着病情进展,腭部、鼻窦、眼眶和皮肤受累会成为警示症状。我们报告一例年轻男性鼻结外NK/T细胞淋巴瘤患者,其症状类似于伴有眼眶并发症的慢性鼻窦炎急性发作。文中讨论了诊断及找到正确治疗途径所面临的挑战。

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本文引用的文献

1
Extranodal NK/T cell lymphoma, nasal type: An updated overview.结外 NK/T 细胞淋巴瘤,鼻型:最新综述。
Crit Rev Oncol Hematol. 2021 Mar;159:103237. doi: 10.1016/j.critrevonc.2021.103237. Epub 2021 Jan 22.
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