• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

纳米脂肪注射治疗凹陷性面部瘢痕。

Nanofat Injection for the Treatment of Depressed Facial Scars.

机构信息

Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 33, Badachu Road, Shijingshan District, Beijing, 100144, China.

出版信息

Aesthetic Plast Surg. 2021 Aug;45(4):1762-1771. doi: 10.1007/s00266-021-02178-7. Epub 2021 Feb 26.

DOI:10.1007/s00266-021-02178-7
PMID:33635346
Abstract

BACKGROUND

Patients with depressed facial scars complain of their negative effects. However, the efficacy of optional treatment techniques is never completely adequate. This study aimed to assess the efficacy of nanofat injection in the improvement of depressed facial scars.

METHODS

This retrospective study included patients who underwent depressed facial scar filling with nanofat between November 2017 and January 2020. The FACE-Q scale was sent to patients for feedback regarding satisfaction. Evaluations of the results were also performed by three plastic surgeons.

RESULTS

Among the 52 included patients, 44 patients (29 women and 15 men) completed the questionnaire. Obvious and stable effects were usually acquired 3 months after surgery. Temporary erythema appeared at the injection site to varying degrees, lasting 2 to 3 weeks in 93% of the patients. No other serious postoperative complications were observed in the injection area. The FACE-Q outcomes showed that patients who completed injection therapy more than 1 year prior were significantly more satisfied with the decision to undergo this therapy than those who completed the treatment less than 1 year prior. Furthermore, according to the physicians' evaluations, 91% of patients experienced improvement in scar appearance after treatment.

CONCLUSIONS

The low rate of injection-site complications and the safety of this procedure both support the current implementation of nanofat in the treatment of depressed facial scars. The results of the physicians' evaluations and patient satisfaction surveys confirmed the stable effect of nanofat injection in the treatment of depressed facial scars.

LEVEL OF EVIDENCE IV

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

摘要

背景

患有凹陷性面部瘢痕的患者会抱怨其负面影响。然而,选择的治疗技术的疗效从未完全充分。本研究旨在评估纳米脂肪注射改善凹陷性面部瘢痕的疗效。

方法

本回顾性研究纳入了 2017 年 11 月至 2020 年 1 月期间接受纳米脂肪填充凹陷性面部瘢痕的患者。患者被发送 FACE-Q 量表以反馈满意度。三位整形医生也对结果进行了评估。

结果

在 52 例纳入的患者中,有 44 例(29 名女性和 15 名男性)完成了问卷调查。术后 3 个月通常会获得明显且稳定的效果。93%的患者注射部位出现不同程度的暂时性红斑,持续 2 至 3 周。在注射部位未观察到其他严重的术后并发症。FACE-Q 结果显示,完成注射治疗 1 年以上的患者对接受这种治疗的决定明显比完成治疗不到 1 年的患者更满意。此外,根据医生的评估,91%的患者在治疗后瘢痕外观得到改善。

结论

注射部位并发症发生率低且该过程安全,这都支持目前将纳米脂肪应用于治疗凹陷性面部瘢痕。医生评估和患者满意度调查的结果证实了纳米脂肪注射治疗凹陷性面部瘢痕的稳定效果。

证据等级 IV:本期刊要求作者为每篇文章指定一个证据等级。如需详细了解这些循证医学等级,请参考目录或在线作者指南www.springer.com/00266。

相似文献

1
Nanofat Injection for the Treatment of Depressed Facial Scars.纳米脂肪注射治疗凹陷性面部瘢痕。
Aesthetic Plast Surg. 2021 Aug;45(4):1762-1771. doi: 10.1007/s00266-021-02178-7. Epub 2021 Feb 26.
2
Comparative Study Using Autologous Fat Grafts Plus Platelet-Rich Plasma With or Without Fractional CO Laser Resurfacing in Treatment of Acne Scars: Analysis of Outcomes and Satisfaction With FACE-Q.自体脂肪移植联合富血小板血浆加或不加非剥脱性二氧化碳激光换肤治疗痤疮瘢痕的对比研究:基于FACE-Q的疗效及满意度分析
Aesthetic Plast Surg. 2017 Jun;41(3):661-666. doi: 10.1007/s00266-017-0777-3. Epub 2017 Jan 26.
3
Unfiltered Nanofat Injections Rejuvenate Postburn Scars of Face.未过滤纳米脂肪注射可改善面部烧伤后瘢痕
Ann Plast Surg. 2019 Jan;82(1):28-33. doi: 10.1097/SAP.0000000000001631.
4
BTX-A Rejuvenation: Regional Botulinum Toxin-A Injection of the Platysma in Patients with Facial Sagging.肉毒素A年轻化治疗:对面部松弛患者的颈阔肌进行局部肉毒素A注射
Aesthetic Plast Surg. 2019 Aug;43(4):1044-1053. doi: 10.1007/s00266-019-01396-4. Epub 2019 May 15.
5
Evaluating the Efficacy of Facial Scar Treatment Techniques Using Nanofat Grafting: A Case Series.评估纳米脂肪移植面部瘢痕治疗技术的疗效:病例系列研究
Cureus. 2024 Sep 6;16(9):e68817. doi: 10.7759/cureus.68817. eCollection 2024 Sep.
6
Scar Assessment After Breast Augmentation Surgery with Axillary Incision versus Inframammary Fold Incision: Long-Term Follow-Up in Chinese Patients.腋窝切口与乳房下皱襞切口隆胸术后瘢痕评估:中国患者的长期随访
Aesthetic Plast Surg. 2016 Oct;40(5):699-706. doi: 10.1007/s00266-016-0671-4. Epub 2016 Aug 2.
7
Does a High-Quality Scar Overcome its Length? Italian Validation of the SCAR-Q Questionnaire.高质量的疤痕是否能弥补其长度?SCAR-Q 问卷的意大利验证。
Aesthetic Plast Surg. 2023 Oct;47(5):2209-2210. doi: 10.1007/s00266-023-03406-y. Epub 2023 May 30.
8
Nanofat Grafting for Scar Treatment and Skin Quality Improvement.纳米脂肪移植用于瘢痕治疗和皮肤质量改善。
Aesthet Surg J. 2018 Mar 14;38(4):421-428. doi: 10.1093/asj/sjx183.
9
Plastic surgery training: evaluating patient satisfaction with facial fillers in a resident clinic.整形手术培训:评估住院医师诊所中患者对面部填充物的满意度。
Aesthetic Plast Surg. 2012 Dec;36(6):1361-6. doi: 10.1007/s00266-012-9973-3. Epub 2012 Sep 18.
10
Isolated neck-lifting procedure: isolated stork lift.单纯颈部提升术:单纯鹳式提升术。
Aesthetic Plast Surg. 2013 Apr;37(2):205-9. doi: 10.1007/s00266-012-0002-3. Epub 2013 Jan 10.

引用本文的文献

1
Advances in the treatment of acne scars.痤疮瘢痕治疗进展
Front Med (Lausanne). 2025 Aug 29;12:1643035. doi: 10.3389/fmed.2025.1643035. eCollection 2025.
2
The Effectiveness of Nanofat in the Management of Skin Scars: A Systematic Review.纳米脂肪在皮肤瘢痕管理中的有效性:一项系统综述
Aesthet Surg J Open Forum. 2025 Jul 2;7:ojaf080. doi: 10.1093/asjof/ojaf080. eCollection 2025.
3
New challenges in scar therapy: the novel scar therapy strategies based on nanotechnology.瘢痕治疗的新挑战:基于纳米技术的新型瘢痕治疗策略。

本文引用的文献

1
Adipose-derived cellular and cell-derived regenerative therapies in dermatology and aesthetic rejuvenation.脂肪来源的细胞和细胞衍生的再生疗法在皮肤科和美容年轻化中的应用。
Ageing Res Rev. 2019 Sep;54:100933. doi: 10.1016/j.arr.2019.100933. Epub 2019 Jun 24.
2
Application of the Stromal Vascular Fraction of Adipose Tissue to a Severe Great Toe Defect Resulting from Third-Degree Electrical Burn Injury.
J Burn Care Res. 2019 Oct 16;40(6):1009-1011. doi: 10.1093/jbcr/irz095.
3
Facial Scar Improvement Procedures.面部瘢痕改善手术。
Nanomedicine (Lond). 2024;19(28):2413-2432. doi: 10.1080/17435889.2024.2401768. Epub 2024 Sep 26.
4
Cytocompatibility Analysis and Comparison of Different Hyaluronic Acid Fillers for Minimally Invasive Esthetics.不同透明质酸填充剂微创美容的细胞相容性分析与比较。
In Vivo. 2024 Jul-Aug;38(4):1621-1635. doi: 10.21873/invivo.13612.
5
Nanofat Accelerates and Improves the Vascularization, Lymphatic Drainage and Healing of Full-Thickness Murine Skin Wounds.纳米脂肪加速和改善全层小鼠皮肤创面的血管化、淋巴引流和愈合。
Int J Mol Sci. 2024 Jan 10;25(2):851. doi: 10.3390/ijms25020851.
6
Mechanical Fractionation of Adipose Tissue-A Scoping Review of Procedures to Obtain Stromal Vascular Fraction.脂肪组织的机械分离——获取基质血管成分的程序的范围综述
Bioengineering (Basel). 2023 Oct 9;10(10):1175. doi: 10.3390/bioengineering10101175.
7
Nanofat in Plastic Reconstructive, Regenerative, and Aesthetic Surgery: A Review of Advancements in Face-Focused Applications.纳米脂肪在整形重建、再生及美容外科中的应用:面部聚焦应用进展综述
J Clin Med. 2023 Jun 28;12(13):4351. doi: 10.3390/jcm12134351.
8
Pressure Masks for Facial Scar Treatment after Oncological Reconstruction: Long-Term Patient Satisfaction and Quality of Life.压力面罩用于肿瘤重建后面部瘢痕治疗:长期患者满意度和生活质量。
Facial Plast Surg. 2024 Feb;40(1):36-45. doi: 10.1055/a-2035-4468. Epub 2023 Feb 14.
9
Nanofat: A therapeutic paradigm in regenerative medicine.纳米脂肪:再生医学中的一种治疗模式。
World J Stem Cells. 2021 Nov 26;13(11):1733-1746. doi: 10.4252/wjsc.v13.i11.1733.
Facial Plast Surg. 2018 Oct;34(5):448-457. doi: 10.1055/s-0038-1669400. Epub 2018 Oct 8.
4
Enhancement of Progenitor Cells by Two-Step Centrifugation of Emulsified Lipoaspirates.两步离心乳化脂肪抽吸物增强祖细胞。
Plast Reconstr Surg. 2018 Jul;142(1):99-109. doi: 10.1097/PRS.0000000000004495.
5
Comparing different nanofat procedures on scars: role of the stromal vascular fraction and its clinical implications.比较不同纳米脂肪程序对瘢痕的影响:基质血管成分的作用及其临床意义。
Regen Med. 2017 Dec;12(8):939-952. doi: 10.2217/rme-2017-0076. Epub 2017 Dec 13.
6
Regenerative Cells For Facial Surgery: Biofilling and Biocontouring.用于面部手术的再生细胞:生物填充与生物轮廓塑造
Aesthet Surg J. 2017 Jul 1;37(suppl_3):S16-S32. doi: 10.1093/asj/sjx078.
7
Use of Condensed Nanofat Combined With Fat Grafts to Treat Atrophic Scars.使用浓缩纳米脂肪与脂肪移植相结合来治疗萎缩性瘢痕。
JAMA Facial Plast Surg. 2018 Mar 1;20(2):128-135. doi: 10.1001/jamafacial.2017.1329.
8
Nanofat 2.0: experimental evidence for a fat grafting rich in mesenchymal stem cells.纳米脂肪2.0:富含间充质干细胞的脂肪移植的实验证据
Physiol Res. 2017 Sep 22;66(4):663-671. doi: 10.33549/physiolres.933451. Epub 2017 Apr 12.
9
Adipose Extracellular Matrix/Stromal Vascular Fraction Gel: A Novel Adipose Tissue-Derived Injectable for Stem Cell Therapy.脂肪细胞外基质/基质血管成分凝胶:一种新型的用于干细胞治疗的脂肪组织衍生可注射材料。
Plast Reconstr Surg. 2017 Apr;139(4):867-879. doi: 10.1097/PRS.0000000000003214.
10
Microneedling: A Comprehensive Review.微针疗法:全面综述
Dermatol Surg. 2017 Mar;43(3):321-339. doi: 10.1097/DSS.0000000000000924.