Brochez Lieve, Volkmer Beate, Hoorens Isabelle, Garbe Claus, Röcken Martin, Schüz Joachim, Whiteman David C, Autier Philippe, Greinert Rüdiger, Boonen Brigitta
Department of Dermatology, Ghent University Hospital, Ghent, Belgium.
Skin Cancer Research Institute Ghent (Skin CRIG), Ghent, Belgium.
J Eur Acad Dermatol Venereol. 2025 Feb;39(2):272-277. doi: 10.1111/jdv.20368. Epub 2024 Oct 8.
One in every three cancers diagnosed is a skin cancer. Europe has the global lead in the number of UV-attributable cancer cases with the highest number of melanoma cases worldwide and the second highest number of keratinocyte cancers (KC). Further increases are expected in Europe for the coming decades. Projected increases are highest for KC with increases in incidence around 40% and increases in mortality around 50%, with KC mortality in males approximating melanoma mortality in females. The two main drivers for this skin cancer epidemic are ageing of the population but especially UV exposure. In conclusion, skin cancer represents a major challenge in the cancer field in Europe today and will continue to do so in the coming decades. This calls for a European skin cancer action plan intended to reduce avoidable UV exposure and to prepare the healthcare system to safeguard early diagnosis and treatment of skin cancer.
每三例确诊的癌症中就有一例是皮肤癌。欧洲在紫外线导致的癌症病例数量方面位居全球之首，黑色素瘤病例数量全球最多，角质形成细胞癌（KC）病例数量全球第二。预计在未来几十年里，欧洲的此类病例还会进一步增加。预计KC的增长幅度最大，发病率将增加约40%，死亡率将增加约50%，男性KC死亡率接近女性黑色素瘤死亡率。导致这场皮肤癌流行的两个主要因素是人口老龄化，但尤其是紫外线暴露。总之，皮肤癌是当今欧洲癌症领域的一项重大挑战，在未来几十年仍将如此。这就需要制定一项欧洲皮肤癌行动计划，旨在减少可避免的紫外线暴露，并让医疗保健系统做好准备，以保障皮肤癌的早期诊断和治疗。
